Foot Infections

Ansari, M. A.; Shukla, Vijay K.

doi:10.1177/1534734605277312

Cited by 10 publications

(3 citation statements)

References 24 publications

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“…Birinci kuşak sefalosporinler (sefaleksin, sefadroksil) ve klindamisin, stafilokok ve streptokoklara karşı iyi etki gösterirler. Şiddetli selüliti olan ve hospitalizasyon gereken hastalarda, parenteral birinci kuşak sefalosporin (sefazolin sodyum gibi) tercih edilebilen antibiyotiklerdendir [16,18].…”

Section: Antibiyoterapiunclassified

Diabetes mellitus and peripheral organs involvement: Current treatment options

Işık

Sarman²,

Şahin³

et al. 2014

J Clin Exp Invest

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Diabetes mellitus is a chronic and multi-systemic disease with various treatment options and has long-term effect on lifestyle of individuals and society. Not only disesase itself but also damage to peripherical organs as a result of disease in long term is an important cause of morbidity and mortality. In this review study it has been aimed to assess complications caused by peripherical organ involvment and treatment options rather than those caused by diabetes mellitus itself.

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Section: Antibiyoterapiunclassified

Diabetes mellitus and peripheral organs involvement: Current treatment options

Işık

Sarman²,

Şahin³

et al. 2014

J Clin Exp Invest

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“…A systematic review of hyperbaric oxygen use in the treatment of chronic wounds found that hyperbaric oxygen can reduce the risk of amputation [31]. HBOT appears to aid in the reduction of bacterial burden by inhibiting anaerobic bacterial growth as well as enhancing antimicrobial properties of leukocytes [32]. These mechanisms would seem apropos in the treatment of DFUs because anaerobic bacteria as well as malfunctioning leukocytes both contribute to the chronicity of these wounds.…”

Section: Reducing the Bacterial Burden In Dfusmentioning

confidence: 99%

The diabetic foot: The importance of biofilms and wound bed preparation

Davis¹,

Martínez²,

Kirsner

2006

Curr Diab Rep

118

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Biofilms are ubiquitous and medically important complex structures consisting of microbial-associated cells embedded in self-produced extracellular matrix of hydrated extrapolymeric substances, which are irreversibly attached to a biological or nonbiological surface. Bacteria that reside as biofilms are resistant to traditional therapy. This alternative community in which microbes exist has recently attracted interest as a potential reason why chronic wounds do not heal. This may be especially important for diabetic foot ulcers, which are often characterized by their refractory nature, their predisposition to have associated underlying infection, and their improvement with débridement. Animal and in vitro models have been developed to better study biofilms, which will allow a venue for therapeutic intervention. Potential opportunities exist that include prevention of bacterial attachment, prevention of biofilm formation, disruption of the biofilm to allow penetration of topical antimicrobial agents, interference with quorum sensing, and enhancement of bacteria dispersion from biofilms to a more easily destroyed planktonic state.

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“…The lower extremity's thin soft tissue envelope is occasionally further compromised by poor vascularity from highenergy trauma, diabetes mellitus, smoking, and peripheral vascular disease. [1][2][3] Standard treatment includes aggressive operative debridement with local and systemic antibiotic administration to control infection. 2,[4][5][6][7] Such debridement can be technically demanding, 7 but the removal of all nonviable tissue is essential to creating a healthy tissue bed and decreasing the infectious load.…”

mentioning

confidence: 99%

Using Cement Plugs in Soft Tissue Infection and Osteomyelitis

Yan¹,

Faro²,

Schon³

2014

Orthopedics

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Operative foot and ankle osteomyelitis is challenging for orthopedic surgeons because of the area’s unique anatomy, high trauma incidence, local and systemic disease effects, and often limited space. Standard treatment includes aggressive operative debridement with local and systemic antibiotic administration to control infection. Dead space management is critical yet technically demanding. The authors report a modified antibiotic cement bead therapy technique in which antibiotic sticks, minnows, and mushroom-shaped plugs are used to strike a balance between the stability of the load-bearing unit and radical removal of infection to preserve a functional foot. Three cases are presented.

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Foot Infections

Cited by 10 publications

References 24 publications

Diabetes mellitus and peripheral organs involvement: Current treatment options

Diabetes mellitus and peripheral organs involvement: Current treatment options

The diabetic foot: The importance of biofilms and wound bed preparation

Using Cement Plugs in Soft Tissue Infection and Osteomyelitis

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