There are many conditions that have the potential to produce the symptom of pain in the metatarsal and midfoot regions. Pathologic processes that cause pain include post-traumatic disorders, circulatory disorders, arthritides, neuroarthropathy, and conditions that result in a biomechanical imbalance in the foot. Magnetic resonance (MR) imaging is a powerful imaging tool since it provides a noninvasive method for diagnosis of different foot disorders. In this article, we will discuss the MR manifestation of a number of pathologic entities that elicit foot pain as a primary symptom.