Force-Extension Curve of a Polymer in a High-Frequency Electric Field

Cohen, Adam E.

doi:10.1103/physrevlett.91.235506

Cited by 26 publications

(14 citation statements)

References 15 publications

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“…This effect was attributed to the global polarizability of a coil at low frequencies [1, 2], and the high local anisotropy of the counterion transport at high frequencies [3, 4]. Here we show that the behavior is drastically different at frequencies at which the counter-ion relaxation length scale matches the scale of internal density fluctuations.…”

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confidence: 72%

Collapse of DNA in ac Electric Fields

et al. 2011

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We report that double-stranded DNA collapses in presence of a.c. electric fields at frequencies of a few hundred Hertz, and does not stretch as commonly assumed. In particular, we show that confinement-stretched DNA can collapse to about one quarter of its equilibrium length. We propose that this effect is based on finite relaxation times of the counterion cloud, and the subsequent partitioning of the molecule into mutually attractive units. We discuss alternative models of those attractive units.

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confidence: 72%

Collapse of DNA in ac Electric Fields

et al. 2011

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“…146-148 A possible mechanism was proposed in Ref. 149 and discussed in detail in Ref. 147, and is illustrated in Fig.…”

Section: Manipulation Of Dna By Electric Fieldsmentioning

confidence: 96%

Molecular Self-Assembly: A Toolkit for Engineering at the Nanometer Scale

Wälti¹

2007

Royal Society Series on Advances in Science

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Among the many challenges facing the development of a molecular-based nanotechnology, the directed assembly of discrete molecular objects, and their controlled integration into macroscopic structures, is fundamental. The selective self-assembly or self-organizing characteristic inherent to certain molecules, for example DNA, is a property that could be exploited to address these challenges. This integration problem can be separated into more fundamental tasks: attaching molecular anchors to the macroscopic structures with high spatial resolution; assembling the discrete molecular objects; and positioning and attaching the molecular objects onto the macroscopic structures.Here, several aspects of these tasks will be discussed, for example using short DNA molecules as molecular anchors and their attachment to electrodes separated by a few ten nanometers; the generation of branched DNA complexes by molecular self-organization; and using AC electric fields for the manipulation, orientation, and positioning of DNA molecules.

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“…23 AC-field induced CGT of P2VP in solutions appears similar to the recent observation of AC-field induced collapse of DNAs, 16 which disagrees with the common consensus that PEs including DNAs can be usually stretched by DC or AC electric fields. 3,4,[25][26][27] However, the mechanism here associated with the AC-electric polarization of annealed hydrophobic PE bearing tunable and mobile charge sites is distinctly different from that with DNA or other quenched PEs bearing fixed charge sites along its backbone: for the latter case, the collapse of pre-stretched DNA is resulted from the anisotropic counterion polarization of DNA chains under micro-or nano-channel confinement; yet for our case, the collapse of P2VP takes places in a bulk solution without spatial confinement and thereby involves a possible mechanism with predominant hydrophobic attraction in comparison to the weakened electrostatic repulsion due to AC-field induced reduction of P2VP charge fraction as further discussed below. Similar behavior of AC-field induced CGT upon decreasing x is also confirmed with P2VP in 1 mM NaCl solution at pH ¼ 4.58 as shown in Fig.…”

Section: A Collapse Without Flow Of P2vp Under Uniform Ac-fieldsmentioning

confidence: 99%

Manipulating single annealed polyelectrolyte under alternating current electric fields: Collapse versus accumulation

Wang

Zhu

2012

Biomicrofluidics

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Effective manipulation and understanding of the structural and dynamic behaviors of a single polyelectrolyte (PE) under alternating current (AC) electric fields are of great scientific and technological importance because of its intimate relevance to emerging bionanotechnology. In this work, we employ fluorescence correlation spectroscopy (FCS) to study the conformational and AC-electrokinetic behaviors of a model annealed PE, poly(2-vinyl pyridine) (P2VP) under both spatially uniform and non-uniform AC fields at a single molecule level. Under spatially uniform AC-fields, we observe a gradual and continuous coil-to-globule conformational transition (CGT) of single P2VP at varied AC-frequency when a critical AC-field strength is exceeded, in contrast to the pH-induced abrupt CGT in the absence of AC-fields. On the contrary, under spatially non-uniform AC-fields, we observe field-driven net flow and accumulation of P2VP near high AC-field regions due to combined AC electro-osmosis and dielectrophoresis but surprisingly no conformational change. Thus, distinct AC-electric polarization effect on single annealed PE subject to AC-field homogeneity is suggested.

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Force-Extension Curve of a Polymer in a High-Frequency Electric Field

Cited by 26 publications

References 15 publications

Collapse of DNA in ac Electric Fields

Collapse of DNA in ac Electric Fields

Molecular Self-Assembly: A Toolkit for Engineering at the Nanometer Scale

Manipulating single annealed polyelectrolyte under alternating current electric fields: Collapse versus accumulation

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