Forecasting Outcomes of Dental Implantation on the Basis of Studying the Level of Products of Oxidative Modification of Saliva Proteins

Aim. Study by the method of electronic paramagnetic resonance (EPR) physical- chemical and structural features of bone tissue and their effect on the processes of osseointegration during dental implantation using implants with different macro-microstructure of the surface. Material and methods. The experimental study was conducted on 7 Vietnamese visobryu-pig mini-pigs. Under anesthesia, implants with different macro-microstructures of the surface (SLA, RBM, ) were installed under the methods of direct and delayed implantation. At different dates of the experiment, after the appropriate anesthesia, the gentle method was to remove implants with small fragments of periemplant bone tissue. Macro-drugs of bone tissue of the jaws after sawing on blocks and extraction of implants, as well as appropriate preparation, were investigated by the method of stationary electronic paramagnetic resonance. Results. As a result of the study it was revealed that the insertation of the implant into the jaw bone leads to structural changes in the surrounding bone implant. After prior exposure, the EPR spectrums, caused by different types of paramagnetic centers, were observed in the samples studied. Two types of centers, , have been identified. and F is the center. The spectrum of the second type reflects the presence in hydroxiapatites of lattice defects associated with isomorphism, and, . The findings suggest that one of the reasons for the higher content of free radicals (SR) in bone tissue derived from radiation, after dental implantation is the weakening of chemical bonds, greater mobility of fragments that make up its structure. It must be assumed that the high content of SR in the bone in the postoperative period is nothing but a result of the disruption of the mineralization process, which is accompanied by the replacement of phosphate groups with carbonate ions that are free-radicalized. It has also been revealed that the structural integrity of the bone depends to a large extent on the degree of orderliness of microcrystals of hydroxyapatite. According to EPR, the most favorable bone recovery (the process of osseointegration) occurs when using implants with a surface, . Conclusions. EPR research of native and carbonate radicals is a unique tool for studying the physical and chemical and structural features of bone tissue and their role in the process of osseointegration of implants. The speed of osseointegration for implants with different microstructures of the surface varies. EPR can be used as an additional method to control the integration of implants into bone tissue.

show abstract

Study by the Method of Elektronic Paramagnetic Resonance of the Infuence of Physics-Chemical and Structural Characteristics of Bone Tissue on the Processes of Osseointegration of Dental Implants With Different Microstructure of the Surface

Chelyshev

Grishin

Savranskiy³

et al. 2021

Actual Problems in Dentistry

View full text Add to dashboard Cite

show abstract

Clinical Studies of the Stability and Process of Osteointegration of Dental Implants During Immediate and Delayed Implantation

Grishin

Kalinnikova

2021

Actual Problems in Dentistry

View full text Add to dashboard Cite

Subject. Analysis of the literature confirms that there is a definite relationship between surface microstructure, implant geometry, thread design and primary stability, and osseointegration processes. To date, a sufficient number of works on direct and delayed implantation have accumulated. However, there is not enough convincing clinical data on the quantitative assessment of primary stability at different periods of the osseointegration process. Despite the existence of experimental and clinical observations, it seems impossible to make a definite judgment about the mechanism of such a relationship. This chapter presents clinical studies of the stability and osseointegration of dental implants when performing, according to the indications, in 414 patients of direct and delayed implantation using implant systems with different surface microstructures. Goal. Conduct clinical studies of quantitative indicators of stability and osseointegration of implants with different microstructure of the surface during direct and delayed implantation. Methodology. For the clinical study of primary stability and the process of osseointegration during direct and delayed implantation with immediate functional loading, implant systems with different surface microstructures were used: Alfa Bio, Mis, Astra-Tech, Dentium, Ostem, Antogher, and also Humana Dental with an innovative surface. Osseointegrated implants have been used to achieve a predictable treatment outcome in clinical cases with partial or complete adentia, as well as in the presence of single, included defects. Results. There were no significant differences in stability indicators at the time of implant placement in the alveolar bone, depending on the type of implant and the method of implantation. Conclusions. In the process of integration of the implant into the bone tissue at a later date, the indicators of stability and osseointegration improve. The relationship between the appearance of the implant surface, primary stability and the time of its adaptation was revealed.

show abstract

Factors Influencing the Long-Term Success of Dental Implantation

Saleev

Grishin

Saleeva

et al. 2021

Actual Problems in Dentistry

View full text Add to dashboard Cite

Aim. To study the role and degree of influence of various clinical factors on osseointegration and the success of direct and delayed dental implantation using implant systems with different surface microstructure. Material and methods. Implant systems with different surface microstructures were used for the clinical study: Alfa Bio, Mis, Astra Tech, Dentium, Osstem, Antogher and Humana Dental. The study included 414 patients aged 20 to 70 years. All patients involved in the study were divided into two groups. The first group consisted of 109 patients who, after extraction, underwent direct implantation into the socket of the extracted tooth, followed by immediate loading. The second group, out of 305 patients, underwent delayed implantation. A total of 1302 implants were installed. Before the start of surgery, all patients underwent a thorough clinical and laboratory, X-ray and functional examination, as well as computed tomography. Dynamic observation was carried out on the basis of clinical, radiological and functional methods. In the course of treatment, starting from the moment of implantation at different times, the devices "Periotest" and "Osstel Mentor" were used to determine the stability of the implants and the dynamics of the quality of the osseointegration process. Results. The study found that implants placed in the lower jaw had higher success rates than implants placed in the upper jaw. There was no direct relationship between the length and diameter of implants and their survival rate. However, implants with a longer length and diameter are the best option for increasing primary stability. The analysis of implantation methods showed no statistically significant difference between the percentage of implant survival during immediate and delayed implantation. The highest percentage of implantation failures was noted with simultaneous implantation and sinus lifting, as well as with a horizontal increase in bone tissue volume. Conclusions. The findings of the study demonstrated that the long-term success of dental implantation depends on a combination of many factors, including bone volume and quality, shape, geometry, implant design, and surface microstructure.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Forecasting Outcomes of Dental Implantation on the Basis of Studying the Level of Products of Oxidative Modification of Saliva Proteins

Cited by 5 publications

References 5 publications

Study by the Method of Elektronic Paramagnetic Resonance of the Infuence of Physics-Chemical and Structural Characteristics of Bone Tissue on the Processes of Osseointegration of Dental Implants With Different Microstructure of the Surface

Study by the Method of Elektronic Paramagnetic Resonance of the Infuence of Physics-Chemical and Structural Characteristics of Bone Tissue on the Processes of Osseointegration of Dental Implants With Different Microstructure of the Surface

Clinical Studies of the Stability and Process of Osteointegration of Dental Implants During Immediate and Delayed Implantation

Factors Influencing the Long-Term Success of Dental Implantation

Contact Info

Product

Resources

About