Foregut motor function in chronic renal failure.

Ravelli, A; Ledermann, Sarah; Bisset, W M; Trompeter, Richard S.; Barratt, T. M.; Milla, Peter J.

doi:10.1136/adc.67.11.1343

Cited by 71 publications

(18 citation statements)

References 17 publications

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“…After renal transplantation gastric dysrhythmias disappeared [134, 135]. Unlike adults [136], children with anorexia nervosa did not show EGG abnormalities [137].…”

Section: Clinical Significance Of Eggmentioning

confidence: 99%

Electrogastrography in Adults and Children: The Strength, Pitfalls, and Clinical Significance of the Cutaneous Recording of the Gastric Electrical Activity

Riezzo

Russo

Indrio

2013

BioMed Research International

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Cutaneous electrogastrography (EGG) is a non-invasive technique to record gastric myoelectrical activity from the abdominal surface. Although the recent rapid increase in the development of electrocardiography, EGG still suffers from several limitations. Currently, computer analysis of EGG provides few reliable parameters, such as frequency and the percentage of normal and altered slow wave activity (bradygastria and tachygastria). New EGG hardware and software, along with an appropriate arrangement of abdominal electrodes, could detect the coupling of the gastric slow wave from the EGG. At present, EGG does not diagnose a specific disease, but it puts in evidence stomach motor dysfunctions in different pathological conditions as gastroparesis and functional dyspepsia. Despite the current pitfalls of EGG, a multitasking diagnostic protocol could involve the EGG and the 13C-breath testing for the evaluation of the gastric emptying time—along with validated gastrointestinal questionnaires and biochemical evaluations of the main gastrointestinal peptides—to identify dyspeptic subgroups. The present review tries to report the state of the art about the pathophysiological background of the gastric electrical activity, the recording and processing methodology of the EGG with particular attention to multichannel recording, and the possible clinical application of the EGG in adult and children.

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“…After renal transplantation gastric dysrhythmias disappeared [134, 135]. Unlike adults [136], children with anorexia nervosa did not show EGG abnormalities [137].…”

Section: Clinical Significance Of Eggmentioning

confidence: 99%

Electrogastrography in Adults and Children: The Strength, Pitfalls, and Clinical Significance of the Cutaneous Recording of the Gastric Electrical Activity

Riezzo

Russo

Indrio

2013

BioMed Research International

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“…A variety of GI symptoms described in CRF patients [1] may be related to esophageal dysmotility, such as heartburn, dysphagia, nausea, and vomiting. Heartburn has been related to Gastroesophageal Reflux Disease (GERD) in these patients [14, 15], while dysphagia is shown to be related to achalasia and esophageal diffuse spasm [2]. None of the motility data observed at the esophageal body level in our patients has been reported as playing a role in GERD, achalasia or diffuse esophageal spasm.…”

Section: Discussionmentioning

confidence: 77%

Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities

et al. 2011

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BackgroundPrevious studies assessing esophageal motility in chronic renal failure (CRF) patients had no consistency in their findings. These studies evaluated esophageal contractility in response to dry/water swallows. Our aim was to reassess esophageal motility in CRF patients to better define its abnormalities. To unmask minor defects not seen in conventional dry/water manometry we also evaluated esophageal contractility in response to a highly viscous substance.MethodsFifteen controls and nine asymptomatic CRF patients underwent esophageal manometry with dry swallows, swallows of 5 mL of water (1 centipoise) and 5 mL of sugar cane syrup (24500 centipoise). CRF patients were compared with controls for esophageal motility parameters, considering each type of swallow (dry/water/syrup).ResultsCRF patients had: tendency for higher lower esophageal sphincter (LES) resting pressure (P = 0.09); shorter LES relaxation duration after dry/water/syrup swallows (P = 0.0001, P < 0.0001, P = 0.0001, respectively); higher amplitude of proximal contractions after dry/water/syrup swallows (P = 0.008, P = 0.01, P = 0.04); tendency for longer duration of distal contractions after dry/water/syrup swallows (P = 0.07, P = 0.04, P = 0.09); lower velocity of distal contractions after dry/water/syrup swallows (P = 0.006, P = 0.09, P = 0.02); and higher incidence of multi-peaked contractions after dry/water/syrup swallows (P = 0.03, P = 0.0001, P < 0.0001).ConclusionsEsophageal motility dysfunction can be a sub-clinical manifestation in CRF patients. Data also showed that swallows of a highly viscous liquid did not help to detect minor esophageal dysmotility in these patients.

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“…Sıkça gözlenen kusma ve dispeptik yakınmalar iştah kaybına, yetersiz kalori alımına sebep olmakta ve çocuklarda büyüme ve gelişmeyi olumsuz etkilemektedir (1,2).…”

Section: Gi Riflunclassified

Kronik Böbrek Yetmezliği Nedeni ile Diyaliz Yapılan Çocuklarda Helikobakter Pilori Enfeksiyonu

Genç¹,

Çaltepe²,

Özkaya³

et al. 2013

Haseki

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1 ÖzetAmaç: Bu çalışmada, kronik böbrek yetmezlikli çocuk hastalarda gastrointestinal semptomlar ile Helicobacter pilori (HP) enfeksiyonu sıklığınının araştırılması planlanmıştır. Yöntem: Çalışmaya kronik böbrek yetmezlikli 33 hasta ile yaş ve cinsiyeti aynı olan sağlıklı kontroller dahil edildi. Hastaların demografik, serolojik ve endoskopik bulguları incelendi ve gastrointestinal sistem semptomları sorgulandı. Çalışmaya dahil edilen tüm hasta ve kontrol grubundan serumda HP-IgG düzeyi çalışıldı. Bulgular: Yirmi yedi periton diyalizi, altı hemodiyaliz hastası çalışmaya dahil edildi. HP seropozitifliği hasta grubunda %51.5, kontrol grubunda %60.6 olarak tespit edildi (p=0.46). Yirmi hastaya özefagogastroduodenoskopi uygulandı ve hastaların %30'unda dokuda HP tespit edildi. Dispepsi tüm hastaların %42.2'sinde belirlendi. Dispeptik hastaların %57.1'inde HP seropozitifliği, %36.4'ünde dokuda HP tespit edildi. Pozitif serolojisi olan hastaların %60'ında dokuda HP gösterilirken, seronegatif olan sadece bir olguda dokuda HP tespit edildi. Sonuç: Toplumumuzda sık görülen ve kolonizasyonu çocukluk yaşlarında başlayan HP enfeksiyonu, çalışmamızda da serolojik olarak hem hasta hem de kontrol grubunda yüksek bulunmuştur. Her biri transplantasyon adayı olan bu hastalar için asemptomatik olsa bile enfeksiyonun saptanması ve tedavisi önem taşımaktadır. Abs tractAim: We aimed to investigate the frequency of gastrointestinal symptoms and Helicobacter pylori (HP) infection in children with chronic renal failure. Methods: The study involved 33 patients with end-stage renal disease and 33 age-and sex-matched healthy controls. Serological, endoscopic and demographic features of the patients were determined and gastrointestinal symptoms were questioned. HP IgG levels were evaluated in all patients and controls. Results: Twenty-seven peritoneal dialysis and 6 hemodialysis patients were included in the study. The HP seropositivity was 51.5% and 60.6% in uremic children and normal controls, respectively (p=0.46). Twenty patients underwent esophagogastroduodenoscopy and HP was detected in 30% of them. Dyspepsia was observed in 42.4% of all patients. In patients with dyspepsia, HP seropositivity rate was 57.1% and biopsy proven HP was 36.4%. Biopsy proven HP was determined in 60% of patients with positive serology and in one with negative serology. Conclusion: HP infection, which is common in our population and begins in early childhood, is found to be frequent in both patient and healthy groups. Even if asymptomatic, it is very important to determine and treat this infection, in these patients who are potential transplant candidates. (The Me di cal Bul le tin of Ha se ki 2013; 51: 1-4)

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Foregut motor function in chronic renal failure.

Cited by 71 publications

References 17 publications

Electrogastrography in Adults and Children: The Strength, Pitfalls, and Clinical Significance of the Cutaneous Recording of the Gastric Electrical Activity

Electrogastrography in Adults and Children: The Strength, Pitfalls, and Clinical Significance of the Cutaneous Recording of the Gastric Electrical Activity

Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities

Kronik Böbrek Yetmezliği Nedeni ile Diyaliz Yapılan Çocuklarda Helikobakter Pilori Enfeksiyonu

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