Foreign body giant cell reaction to silicone oil presenting as a salmon-patch conjunctival lesion

Azarcon, Corrina P.; Grossniklaus, Hans E.; Wells, Jill R.

doi:10.1016/j.ajoc.2022.101676

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…However, silicone oil infiltration was not seen in the biopsied conjunctival tissue. Possible slow gradual leakage of in the Several studies [8][9][10][11] have shown that the migration of silicone oil bubbles in the subconjunctival tissue initiates chronic inflammatory process evident by presence of histio-cytes and multinucleated lymphocytes. This suggests granulomatous inflammatory reaction to silicone oil.…”

Section: Discussionmentioning

confidence: 99%

Conjunctival Pigmentation at the Sclerotomy Site following 23 G Vitrectomy with Silicone Oil Injection

Hussain

2022

Case Reports in Ophthalmological Medicine

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54-year-old gentleman undergoing 23 Gauge vitrectomy with silicone oil injection developing conjunctival pigmentation at one of the entry sites of trocar and cannula 1 week postoperative. The conjunctival tissue was biopsied at the time of silicone oil removal and correlated histopathological. Biopsy of the conjunctival tissue showed intracellular and stromal melanin pigments. This report highlights conjunctival pigmentation in suture less entry site and silicone oil as intraocular tamponade than earlier published reports of with or without intraocular gas tamponade.

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Section: Discussionmentioning

confidence: 99%

Conjunctival Pigmentation at the Sclerotomy Site following 23 G Vitrectomy with Silicone Oil Injection

Hussain

2022

Case Reports in Ophthalmological Medicine

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Silicone on the Move: Migratory Siliconoma After Retinal Surgery Report of a Case and Review of the Literature

Finkelstein,

Pukhalskaya,

North

et al. 2024

The American Journal of Dermatopathology

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Silicone granulomas, or “siliconomas,” are the common foreign-body inflammatory responses to injected silicone material. In rare cases, siliconomas develop remotely from the original site of injection, secondary to silicone migration. If a history of silicone injection is not noted, such lesions risk misdiagnosis (possibly as infection or malignancy). Intraocular silicone oil is commonly used in retinal detachment surgery, with occasional reports of granulomatous responses after its application in this context. Here, we report a 66-year-old man who developed a periocular silicone granuloma years after scleral buckle surgery for a detached retina and summarize the literature of similar reports of migratory siliconoma.

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Foreign body giant cell reaction to silicone oil presenting as a salmon-patch conjunctival lesion

Cited by 2 publications

References 11 publications

Conjunctival Pigmentation at the Sclerotomy Site following 23 G Vitrectomy with Silicone Oil Injection

Conjunctival Pigmentation at the Sclerotomy Site following 23 G Vitrectomy with Silicone Oil Injection

Silicone on the Move: Migratory Siliconoma After Retinal Surgery Report of a Case and Review of the Literature

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