The aim of the study is to elaborate an econometric model to determine the conditions for ensuring the balanced development of environmental, economic, and social components of the Russian agricultural sector within the Eastern European region. The method of fuzzy sets was used to build an integral model for assessing the level of sustainable development of the agricultural sector in Eastern Europe on the basis of economic, environmental, and social sustainability indicators. The control indicators (independent variables) and integral economic, environmental, social sustainability (dependent variables) helped build multifactor linear regression models and calculate the indicators of elasticity of dependent variables from independent variables, which characterize the change in sustainable development indicators with the growth of controlling factors by 1%. This model allows us to define and analyze the levels of sustainable development of the industry, both in a specific country and within the region in general. The study shows that, for Russia and Eastern European countries, innovation is one of the crucial factors in ensuring sustainable development of agriculture in the region, taking into account the current state and level of economic development.