Forensic Aspects of Horseracing

Abstract

The sport of horseracing has a long history, including a strong association with betting. This association, in particular, has introduced the risk of corruption, which is controlled by regulation. Challenges faced by regulators include assuring horse identity, controlling doping and medication, preventing prohibited practices, assuring horse welfare, and controlling corrupt betting. Forensic tools used to aid regulators include visual methods of identification, electronic ID transponders, DNA technology for parentage verification, laboratory analysis for drug detection, and modern intelligence and analysis tools

Plasma and urine pharmacokinetics of two formulations of dexamethasone in greyhound dogs

“…For medication control of drugs for animals used in sport, urine is the sample matrix of choice (Morris, 2014). To inform risk assessment for medication control, information on contemporaneous plasma (as plasma levels drive effects) and urine levels, after clinical…”

“…For medication control of drugs for animals used in sport, urine is the sample matrix of choice (Morris, 2014). To inform risk assessment for medication control, information on contemporaneous plasma (as plasma levels drive effects) and urine levels, after clinical doses of the formulations used by clinicians, that define the terminal elimination phases, and with limits of quantification that are appropriate for medication control rather than therapeutics, is required.…”

“…Dexamethasone in plasma was measured for 10 h after administration, and the limit of quantification (LOQ) was 2 ng/ml. 1 mg of an undefined formulation of dexamethasone was injected intramuscularly into 25 greyhounds, and urine samples collected for up to 96 h (Hill et al, 1997) with dexamethasone being detected for 24 h.For medication control of drugs for animals used in sport, urine is the sample matrix of choice (Morris, 2014). To inform risk assessment for medication control, information on contemporaneous plasma (as plasma levels drive effects) and urine levels, after clinical…”