Foreskin healing after distal hypospadias repair: Does stenting affect the outcome?

Honkisz, Ireneusz; Sulisławski, Janusz; Dobrowolska-Glazar, Barbara; Kuijper, Caroline F.; Chrzan, Rafał

doi:10.17219/acem/127677

Cited by 2 publications

(1 citation statement)

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“…Hypospadias is a common congenital malformation of the genitourinary tract in male children, accounting for 0.3%~0.5% of newborn boys, and still has an increased incidence recently [10]. Among them, distal penile hypospadias accounts for about 70% of all cases of hypospadias [11]. As a multifactorial disease, hypospadias may occur owing to the impact of heredity factors, environmental factors, hormone regulation, gene mutations, etc.…”

Section: Discussionmentioning

confidence: 99%

Clinical Value of Microsurgery Combined with Covering New Urethra by Multilayer Sarcolemma Tissues in the Treatment of Hypospadias in Male Children and Analysis of Urodynamic Parameters

Zheng,

Guo,

Shi

et al. 2024

Preprint

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Objective To compare and analyze differences in the clinical effect and postoperative urodynamic indexes of microsurgery combined with covering new urethra by multilayer sarcolemma tissues and conventional surgery alone in the treatment of male children with hypospadias. Methods A total of 80 male children with penile hypospadias who were hospitalized in Beijing Children's Hospital Affiliated to Capital Medical University Baoding Hospital were randomly divided into two groups, with 40 in each group. Children in the study group underwent microsurgery combined with covering new urethra by multilayer sarcolemma tissues, while those in the control group were provided with traditional tubularized incised plate (TIP) urethroplasty alone. Further comparative analysis was performed on the operation effect, operation time, total intraoperative bleeding, postoperative length of stay in the hospital and the incidence of surgical complications between the two groups. All male children were followed up for 6 months to compare and analyze the changes of urodynamic parameters such as maximum urinary flow rate (Qmax), mean urinary flow rate (Qavc), post-void residual urine (PVR) before and after surgery. Results There were statistically significant differences that the operation time(p = 0.03) was longer while the postoperative length of stay in the hospital (p = 0.000) was shorter in the study group than those in the control group. The effective rate of the study group was 97.50%, while that of the control group was 82.50%, with statistically significant difference (p = 0.025). The incidence of surgical complications was 7.50% in the study group and 25.00% in the control group 3 months after operation (p = 0.034). There was statistically significant difference that the Hose score of the study group was significantly higher than that of the control group (p = 0.000). Meanwhile, there was no significant difference in indicators such as Qmax, Qavc and PVR between the two groups before surgery; while the levels of Qmax and Qavc in the study group were higher than those in the control group 6 months after surgery, with statistically significant difference (p = 0.000). Conclusion Microsurgery combined with covering new urethra by multilayer sarcolemma tissues has certain clinical value in the treatment of male children with hypospadias, which shows good therapeutic effect, shorter length of stay in the hospital, lower incidence of postoperative complications, and significantly improved urodynamic indicators, despite slightly complicated operation and relatively longer duration of operation.

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Section: Discussionmentioning

confidence: 99%