2019
DOI: 10.1007/978-3-030-17910-6_10
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Formal Analysis of Robotic Cell Injection Systems Using Theorem Proving

Abstract: Cell injection is an approach used for the delivery of small sample substances into a biological cell and is widely used in drug development, gene injection, intracytoplasmic sperm injection (ICSI) and in-virto fertilization (IVF). Robotic cell injection systems provide the automation of the process as opposed to the manual and semi-automated cell injection systems, which require expert operators and involve time consuming processes and also have lower success rates. The automation of the cell injection proces… Show more

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Cited by 5 publications
(8 citation statements)
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“…Moreover, the authors used these formalizations for formally analyzing an automobile suspension system, a MEMs accelerometer and a 4 − π soft-error crosstalk model [36,39]. Similarly, Rashid et al [34,38] formally verified a cell injection system upto 4-DOF using HOL Light. The authors verified various coordinate systems and their interrelationship, which are vital for capturing the position and relative movement of a robotic cell injection system.…”
Section: Related Workmentioning
confidence: 99%
See 1 more Smart Citation
“…Moreover, the authors used these formalizations for formally analyzing an automobile suspension system, a MEMs accelerometer and a 4 − π soft-error crosstalk model [36,39]. Similarly, Rashid et al [34,38] formally verified a cell injection system upto 4-DOF using HOL Light. The authors verified various coordinate systems and their interrelationship, which are vital for capturing the position and relative movement of a robotic cell injection system.…”
Section: Related Workmentioning
confidence: 99%
“…HOL Light is built using the functional programming language objective CAML (OCaml). It has been extensively used for the formal verification of both hardware [8,34,49] and software systems [46] along with the formalization of mathematics.…”
Section: Hol Light Theorem Provermentioning
confidence: 99%
“…The authors mainly formalized the safety zone of the robot based on the algorithm and used it to formally verify that the robot will stop upon facing an obstacle, otherwise, it will continue its movement within the safety zone. Recently, Rashid et al [80] provided the formal modeling and analysis of the 2-DOF robotic cell injection systems using HOL Light.…”
Section: Verification Of Control and Signal Processing Componentsmentioning
confidence: 99%
“…Later, Affeldt et al [43] extended this framework by formalizing the foundations for analyzing three-dimensional robot manipulator using the Coq theorem prover [44] and used it for the verification of the SCARA robot manipulator. Recently, Rashid and Hasan [45] provided the formal modeling and analysis of the 2-DOF robotic cell injection systems using HOL Light. However, to the best of our knowledge, higher-order-logic based theorem proving has never been used in the context of macroscopic models, which is the scope of the current paper.…”
Section: Related Workmentioning
confidence: 99%