Complex adaptive systems provide a significant number of concepts such as reaction, interaction, adaptation, and evolution. In general, these concepts are modelled employing different techniques which give an inexplicit vision on the system. Therefore, all concepts must be carefully modelled using the same approach to avoid contradiction and guarantee system homogeneity and correctness. However, developing a computing system that includes all these concepts using the same approach is not an easy task and requires a perfect understanding of the system’s behaviour. In this paper, we contribute as stepwise towards proposing an approach to model the most important concepts of complex adaptive systems while ensuring homogeneity and the correctness of models. For this aim, we present five standard agent-based models formalizing agent properties, reaction, interaction, adaptation, and evolution. These models are adapted to all cases of complex adaptive systems since they include an abstract description of these concepts. To implement our approach formally, we choose the Event-B method due to the strong assurance of bugs’ absence that it guarantees. Besides, it supports horizontal and vertical refinement which facilitates the specification process. Furthermore, the approach of this paper addresses the very abstract level of modelling which expand the use of this approach to other formal methods and tools.