Rising global temperature has triggered the cooling demand in the last three decades with growing predictions for the future. The use of conventional energy-intensive and high global warming chemical-based cooling systems is working in a loop, increasing the global warming rate, emissions, and cooling system inventory. Therefore, the development of an innovative cooling system with high energy efficiency, low monetary cost, and environmentally sustainable. The indirect evaporative cooling-based systems have shown potential to serve the purpose because of low energy consumption, absence of energy, and cost-intensive equipment like compressors and water-based operation. A novel indirect evaporative cooler based on an innovative operational configuration is proposed, fabricated, and tested experimentally. The Proposed system has several advancements compared to the conventional indirect evaporative coolers like high operational reliability, low maintenance, and better control of the processes in the system. The study shows that the proposed system can achieve a temperature drop of as high as 14°C. The maximum cooling capacity of the system is calculated as 110 W, and the cooling performance index of 28. The performance of the cooler improves with increasing outdoor air temperature which makes it suitable for diverse climatic conditions. Moreover, the proposed design offers several benefits due to novel operational configurations by addressing limitations in the earlier systems.