Formation and detection of biocoronas in the food industry and their fate in the human body

Wu, Qian; Niu, Mengyao; Zhou, Chen; Wang, Yaxiong; Xu, Jianhua; Shi, Lin; Xiong, He; Feng, Nianjie

doi:10.1016/j.foodres.2023.113566

Cited by 1 publication

(1 citation statement)

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“…The formation of a dynamic biocorona (see Fig. 1 ) is a characteristic of ENM present in biological fluids and can influence the toxicological properties of the nanoparticles, as extensively shown and reviewed in literature [ 14 – 20 ]. For instance, macrophages and other innate immune cells respond to the biocorona-dependent biological identity of nanomaterials rather than to their synthetic identity [ 18 ].…”

Section: Asnp Fate In the Gastrointestinal Tract: Physico-chemical Mo...mentioning

confidence: 99%

Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications

Bianchi,

Chiu,

Taurino

et al. 2024

J Nanobiotechnol

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Amorphous silica nanoparticles (ASNP) are among the nanomaterials that are produced in large quantities. ASNP have been present for a long time in several fast-moving consumer products, several of which imply exposure of the gastrointestinal tract, such as toothpastes, food additives, drug excipients, and carriers. Consolidated use and experimental evidence have consistently pointed to the very low acute toxicity and limited absorption of ASNP. However, slow absorption implies prolonged exposure of the intestinal epithelium to ASNP, with documented effects on intestinal permeability and immune gut homeostasis. These effects could explain the hepatic toxicity observed after oral administration of ASNP in animals. More recently, the role of microbiota in these and other ASNP effects has attracted increasing interest in parallel with the recognition of the role of microbiota in a variety of conditions. Although evidence for nanomaterial effects on microbiota is particularly abundant for materials endowed with bactericidal activities, a growing body of recent experimental data indicates that ASNPs also modify microbiota. The implications of these effects are recounted in this contribution, along with a discussion of the more important open issues and recommendations for future research. Graphical Abstract

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Section: Asnp Fate In the Gastrointestinal Tract: Physico-chemical Mo...mentioning

confidence: 99%

Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications

Bianchi,

Chiu,

Taurino

et al. 2024

J Nanobiotechnol

View full text Add to dashboard Cite

show abstract

Formation and detection of biocoronas in the food industry and their fate in the human body

Cited by 1 publication

References 140 publications

Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications

Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications

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