Formation of aminium lactates in lactic acid fermentation preparation and characterization of 1,4‐piperazinium‐(L,L)‐dilactate obtained fromL(+)‐lactic acid (part I)

Abstract

The potential for the production of 1.4-piperazinium-(L, L)-dilactate from L(+)-lactic acid preparations obtained by fermentation was studied. Piperazinium dilactate was found to be a very suitable source material for poly(1actic acid) production. In a novel polymerization process, the intermediate dilactide was directly formed in the salt melt at a moderate temperature. High-performance cultivation of Lucrobocillus pumcawi on a glucose-MRS medium was carried out using high-viability inocula. After the cell mass had been removed from the fermentation broth by centrifugation and/or ultrafiltration, the lactic acid solution was concentrated to 45% [wlw] by ; 1 two-stage electrodialysis process. Two methods of preparing 1,4-piperazinium dilactate were developed: the first from the medium-concentrated lactic acid ( 4 5 4 ) and the second from a highly-concentrated lactic acid (85%) obtained by evaporation from the first one. Because there were no physical data on 1,4-piperazinium-(l, L)-dilactate in specialized literature, the pure product was characterized according to its solubility characteristics. melting point and spectroscopic analysis.

Renewable resources – green biorefinery: separation of valuable substances from fluid–fractions by means of membrane technology

“…17,[31][32][33][34] In addition, it has been widely applied for the production of table salt, organic acids, sugar and whey demineralization, recovery of metal from mining-mill process water as well as for blood treatment and wine stabilization. [45][46][47][48][49][50][51][52][53][54] Th erefore this technology seems to be suitable for separating minerals and lactic acid from green press-juice.…”

“…[15][16][17] Table 1 shows that silage press-juice as well as Lactobacillus paracasei fermented brown juice contain an acceptable concentration of lactate.…”

Novel extractants for the recovery of fermentation derived lactic acid

“…Based on the adsorption results, any of the three multiple-nitrogen-functional groups could be potentially good for extracting LA, and the observed temperature effect in the distribution also offers good opportunities for an efficient back-extraction. However, because of recoverability issues observed by Kamm et al [21,22] and Thomsen [23] working with piperazines and LA, it was decided not to develop an extractant with this functional group, but to focus on DMAP and TBD-based extractants.…”

Fermentative Production of Piperazinium Dilactate

“…From the latter, polylactides are manufactured by ringopening polymerization. In an earlier paper [6], we reported on preparing piperazinium dilactate in a combined process that included common lactic acid fermentation and a chemical neutralization reaction. By contrast, dilactide is formed in a single step when aminium lactates are used as starting material [5].…”