ƒÀ-tricalcium bis (orthophosphate) [Ca3(PO4)2] (ƒÀ-TCP) was mechanochemically treated with mortar grinder. The ground ƒÀ-TCP was hydrolyzed in organic-aqueous binary systems (octane-H2O , and octanol-H2O) to give Ca-deficient hydroxyapatite (HAp) involving small amount of CO32-ions. The rate of the hydrolysis in octane-H2O binary system was faster than that in ammonium aqueous solution , however, shape of the products in the binary system did not so much differ from that in the aqueous system. Fluorination of the ground p-TCP proceeded much faster than that of ƒÀ-TCP to form fluoridated hydroxyapatite (FHAp) .