Formation, thermodynamic properties, microstructures and antimicrobial activity of mixed cationic/non-ionic surfactant microemulsions with isopropyl myristate as oil

Bardhan, Soumik; Kundu, Kaushik; Das, Sajal; Poddar, Madhumita; Saha, Swapan K.; Paul, Bidyut K.

doi:10.1016/j.jcis.2014.05.042

Cited by 25 publications

(23 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, a wide variety of nanotechnological‐based approaches including microemulsions, inorganic, vaccines, metallic, lipid, and polymeric‐based nanoparticles (NPs) have been developed for the treatment of infectious diseases. Gold nanoparticles (AuNPs) show considerably distinct chemical, physical, and biological properties because of their high surface‐to‐volume ratio, with which surfaces can be modified with ligands containing functional groups, providing steric or an electrostatic stabilization .…”

Section: Introductionmentioning

confidence: 99%

Antibacterial effects of gold nanoparticles functionalized with the extracted peptide from Vespa orientalis wasp venom

Jalaei

Layeghi-Ghalehsoukhteh

Hosseini

et al. 2018

Journal of Peptide Science

View full text Add to dashboard Cite

The development of novel antimicrobial strategies is necessary because of the escalation of multidrug‐resistant pathogens. Recently, antimicrobial peptides and their combination with nanoparticles were regarded as a promising tool to target drug‐resistant pathogens. Herein, we evaluated antimicrobial efficacy of a peptide extracted from Vespa orientalis wasp venom and also its conjugation with gold nanoparticles. Nanoparticle conjugation measurement was done by evaluating the absorbance changes of the surface plasmon resonance band of gold nanoparticles at 555 nm. A significant increase in the antibacterial activity against gram negative and positive bacteria was obtained when the extracted peptide conjugated with gold nanoparticles. Finally, the results show that this new peptide‐AuNps has the high practical potential for antibacterial activity and may provide an alternative therapy for bacterial infection.

show abstract

Section: Introductionmentioning

confidence: 99%

Antibacterial effects of gold nanoparticles functionalized with the extracted peptide from Vespa orientalis wasp venom

Jalaei

Layeghi-Ghalehsoukhteh

Hosseini

et al. 2018

Journal of Peptide Science

View full text Add to dashboard Cite

show abstract

“…The deconvolution of the FTIR spectra is displayed in Figure b–e for pure BHDC and pure AOT as well as those in the presence of Brij‐30. According to the “three states model”, the water in the nanoscopic domain of reverse micelles is identified as free water (FW), bound water (BW), and trapped water (TW) molecules . The FW molecules (≈2450 cm −1 ) occupying the cores of the water pool of the reverse micelles engage in strong hydrogen‐bonding interactions with the neighboring water molecules.…”

Section: Resultsmentioning

confidence: 99%

“…According to the "three states model", the water in the nanoscopic domain of reversem icelles is identified as free water (FW), bound water (BW), and trapped water (TW) molecules. [36] The FW molecules ( % 2450 cm À1 )o ccupying the cores of the water pool of the reverse micelles engage in stronghydrogen-bonding interactions with the neighboringw ater molecules. The second component peakinga ta pproximately 2545 cm À1 involves the so-called bound water (BW) molecules,i ncapable of forming fullyd eveloped hydrogen bonds and bound to the surfactant headgroups.T he third type of water moleculesa bsorbing in the high-frequency region ( % 2640 cm À1 )i sg enerally dispersed among the long hydrocarbonc hains of the surfactant molecules.…”

Section: Resultsmentioning

confidence: 99%

Modulation of Kinetic Pathways of Enzyme–Substrate Interaction in a Microfluidic Channel: Nanoscopic Water Dynamics as a Switch

Singh

Mukherjee

Singha

et al. 2019

Chemistry A European J

View full text Add to dashboard Cite

Enzyme‐mediated catalysis is attributed to enzyme–substrate interactions, with models such as “induced fit” and “conformational selection” emphasizing the role of protein conformational transitions. The dynamic nature of the protein structure, thus, plays a crucial role in molecular recognition and substrate binding. As large‐scale protein motions are coupled to water motions, hydration dynamics play a key role in protein dynamics, and hence, in enzyme catalysis. Here, microfluidic techniques and time‐dependent fluorescence Stokes shift (TDFSS) measurements are employed to elucidate the role of nanoscopic water dynamics in the interaction of an enzyme, α‐Chymotrypsin (CHT), with a substrate, Ala‐Ala‐Phe‐7‐amido‐4‐methylcoumarin (AMC) in the cationic reverse micelles of benzylhexadecyldimethylammonium chloride (BHDC/benzene) and anionic reverse micelles of sodium bis(2‐ethylhexyl)sulfosuccinate (AOT/benzene). The kinetic pathways unraveled from the microfluidic setup are consistent with the “conformational selection” fit for the interaction of CHT with AMC in the cationic reverse micelles, whereas an “induced fit” mechanism is indicated for the anionic reverse micelles. In the cationic reverse micelles of BHDC, faster hydration dynamics (≈550 ps) aid the pathway of “conformational selection”, whereas in the anionic reverse micelles of AOT, the significantly slower dynamics of hydration (≈1600 ps) facilitate an “induced fit” mechanism for the formation of the final enzyme–substrate complex. The role of water dynamics in dictating the mechanism of enzyme–substrate interaction becomes further manifest in the neutral reverse micelles of Brij‐30 and Triton X‐100. In the former, the faster water dynamics aid the “conformational selection” pathway, whereas the significantly slower dynamics of water molecules in the latter are conducive to the “induced fit” mechanism in the enzyme–substrate interaction. Thus, nanoscopic water dynamics act as a switch in modulating the pathway of recognition of an enzyme (CHT) by the substrate (AMC) in reverse micelles.

show abstract

“…Interfacial arrangements or organizations of the constituents at the interface were found to be mostly affected by increase in temperature in the vicinity of equimolar composition compare to other compositions. However, a correlation between composition-dependent antibacterial activities on the growth of both bacterial strains with the spontaneity of formation with regard to thermodynamic stability of the microemulsion systems was exhibited under the prevalent conditions [36].…”

Section: Findings Analysis and Interpretation Dilution Study With Simentioning

confidence: 98%

“…Moreover, quantitative description of the dependence of the partition equilibrium [particularly in respect of (2)] on the system composition deserves for a full understanding of quaternary systems [26,32]. All these parameters [except (4), which can be determined from Fourier transform infrared spectroscopy, FTIR measurements] [33][34][35][36], can be evaluated from the dilution method without using sophisticated instruments. The pioneering work for characterizing water-in-oil microemulsions systems is due to Bowcott and Schulman [37].…”

Section: Introductionmentioning

confidence: 99%

The Schulman Method of Cosurfactant Titration of the Oil/Water Interface (Dilution Method): A Review on a Well‐Known Powerful Technique in Interfacial Science for Characterization of Water‐in‐Oil Microemulsions

Bardhan

Kundu

Chakraborty

et al. 2015

J Surfact & Detergents

Self Cite

View full text Add to dashboard Cite

Microemulsions are thermodynamically stable, isotropic transparent mixtures of two immiscible liquids (polar and nonpolar) and amphiphile(s) (usually surfactant and/or cosurfactant). The cosurfactant plays an important role by blending with surfactants, and partitioned between the coexisting aqueous and oleic phases to control the bending elasticity of the interfacial layer to render stability to the dispersion. The microheterogeneity of such dispersions makes them useful in biological and technological applications. Various techniques viz., conductance, interfacial tension, SANS etc. were applied to estimate the distribution of cosurfactant between the interface and the bulk oil. However, a simple but ingenious method comprising repetitively oil dilution with cosurfactant titration till attainment of stable microemulsions was also used to measure the distribution of cosurfactant. This review summarizes formation and characterization of water-in-oil microemulsions stabilized by single or mixed surfactants of different charge types and polar head groups or mixed surface active ionic liquid and surfactant, and cosurfactants of different lipophilicities in both hydrocarbons and long chain alkyl ester oil, emphasizing interfacial composition, thermodynamics of formation and structural parameters by the dilution method coupled with transport properties, microstructures and states of water organization inside the pool etc. using instrumental techniques. Applicability of the data obtained from dilution method in different areas, viz. nanomaterial synthesis, enzyme activity, etc. have been reported. Indeed, this article presented a journey of development and significant contribution in utilizing this elegant and inexpensive method to accomplish the formation of microemulsion through consistent motivation by researchers of different countries.

show abstract

Formation, thermodynamic properties, microstructures and antimicrobial activity of mixed cationic/non-ionic surfactant microemulsions with isopropyl myristate as oil

Cited by 25 publications

References 65 publications

Antibacterial effects of gold nanoparticles functionalized with the extracted peptide from Vespa orientalis wasp venom

Antibacterial effects of gold nanoparticles functionalized with the extracted peptide from Vespa orientalis wasp venom

Modulation of Kinetic Pathways of Enzyme–Substrate Interaction in a Microfluidic Channel: Nanoscopic Water Dynamics as a Switch

The Schulman Method of Cosurfactant Titration of the Oil/Water Interface (Dilution Method): A Review on a Well‐Known Powerful Technique in Interfacial Science for Characterization of Water‐in‐Oil Microemulsions

Contact Info

Product

Resources

About