Former poliomyelitis as a health and socioeconomic factor. A paired sibling study

Farbu, Elisabeth; Gilhus, Nils Erik

doi:10.1007/s004150200030

Cited by 13 publications

(13 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…None of the examined patients needed to move into institutions. The number of patients employed were lower than in a previous cohort‐based study, and also in a hospital‐based polio population in Bergen (Farbu and Gilhus, 1997, 2002). The patients’ experience of increasing symptoms and functional decline explain this; they seek medical examination and treatment when the symptoms and reduced function limit their daily life and participation in professional life.…”

Section: Discussionsupporting

confidence: 87%

See 1 more Smart Citation

Post‐polio syndrome and total health status in a prospective hospital study

Farbu

Rekand

2003

Euro J of Neurology

View full text Add to dashboard Cite

New loss of function among patients with previous polio is frequently reported and has several causes. All patients referred to the Department of Neurology, Haukeland University Hospital, Bergen, for 13 months during 2000-2001 with diagnosis late effects of polio were examined prospectively to identify their symptoms and loss of function. Eighty-five patients aged 47-91 years with mean of 61 years were included. The most common complaints were pain (44%), muscular weakness (27%), and fatigue (16%). Muscular weakness occurred in lower limbs in 75%, in respiratory muscles in only 5%. Walking in stairs was impaired in 72% and outdoor walking in 65%. Seventeen patients (19%) reported no loss of function. Post-polio syndrome was diagnosed in 26% of the patients. Polio-related loss of function including cervical and lumbosacral radiculopathies, mononeuropathies and degenerative joint disease were found in an additional 53%. Eleven patients (13%) had distinct non-polio-related disorders that caused new loss of function. The remaining 8% had a stable condition. In conclusion, the majority of polio patients who seek hospital, experience a new loss of function because of polio-related disorders. A careful neurological examination is necessary to identify the correct diagnosis and treatment.

show abstract

Section: Discussionsupporting

confidence: 87%

“…, 1999; March of Dimes, 2000; Rekand et al. , 2000; Farbu and Gilhus, 2002). However, our patients presented with distinct patterns of pain, mainly intrinsic muscular pain in apparently non‐paralytic muscles.…”

Section: Discussionmentioning

confidence: 87%

Post‐polio syndrome and total health status in a prospective hospital study

Farbu

Rekand

2003

Euro J of Neurology

View full text Add to dashboard Cite

show abstract

“…The prevalence of PPS was reported to range from 15% to 80% because of differences in the criteria applied and the population studied [13,20,21,22,23,24]. These results demonstrated that 78.0% of the total subjects developed at least one symptom, such as fatigue, pain, or weakness after a long period of stabilization following acute poliovirus infection and 61.6% of the subjects met the clinical diagnostic criteria for PPS.…”

Section: Discussionmentioning

confidence: 99%

Post-Polio Syndrome and Risk Factors in Korean Polio Survivors: A Baseline Survey by Telephone Interview

et al. 2014

View full text Add to dashboard Cite

ObjectiveTo obtain information on the socioeconomic, medical, and functional status of polio survivors, and to use these results as the preliminary data for establishing the middle-aged cohort of polio survivors.MethodsThe subjects were recruited based on the medical records of multiple hospitals and centers. They were assessed through a structured questionnaire over the phone. Post-poliomyelitis syndrome (PPS) was identified according to the specified diagnostic criteria. Differences between polio survivors with or without PPS were evaluated, and the risk factors for PPS were analyzed by the odds ratio (OR).ResultsMajority of polio survivors were middle-aged and mean age was 51.2±8.3 years. A total of 188 out of 313 polio survivors met the adopted criteria for PPS based on the symptoms, yielding a prevalence of 61.6%. Mean interval between acute poliomyelitis and the development of PPS was 38.5±11.6 years. Female gender (OR 1.82; confidence interval [CI] 1.09-3.06), the age at onset of poliomyelitis (OR 1.75; CI 1.05-2.94), the use of orthoses or walking aids (OR 2.46; CI 1.44-4.20), and the history of medical treatment for paralysis, pain or gait disturbance (OR 2.62; CI 1.52-4.51) represented independent risk factors for PPS.ConclusionWe found that the majority of Korean polio survivors entered middle age with many medical, functional, and social problems. Female gender, early age of onset of poliomyelitis, the use of orthoses or walking aids, and the history of medical treatment for paralysis, pain or gait disturbance were identified as the significant risk factors for PPS. A comprehensive and multidisciplinary plan should be prepared to manage polio survivors considering their need for health care services and the risk factors for late effects, such as PPS.

show abstract

“…In the acute phase of PM, only spasms were described [18][19][20]. Following the acute PM attack, cramps and fasciculations were reported with prevalences of about 50% [16,21,22]. We found that, late in life, these muscle symptoms were reported by a total of 43%.…”

Section: Discussionmentioning

confidence: 59%

Neurological Symptoms in Danes with a History of Poliomyelitis: Lifelong Follow-Up of Late Symptoms, their Association with Initial Symptoms of Polio, and Presence of Postpolio Syndrome

Kay¹,

Nielsen

Wanscher

et al. 2018

Eur Neurol

View full text Add to dashboard Cite

Background: Previous studies suggest that patients with a history of poliomyelitis (PM) later in life experience a variety of symptoms. These studies were carried out in patients who later in life were admitted to hospital or became members of polio societies and may therefore not be representative of all polio patients. Little data have been published concerning patients actually discharged from hospital with a diagnosis of acute paralytic PM. Objectives: The aim of this study was to compare the prevalence of late symptoms in individuals with a history of paralytic PM with that of controls, and to study whether late symptoms in individuals with a history of PM were associated with symptoms at the acute stage of polio, and finally to compare the prevalence of symptoms in polio patients with postpolio syndrome (PPS) with the prevalence of symptoms in polio patients without PPS. Methods: A questionnaire concerning various symptoms was sent to a previously established cohort of patients, who during the polio epidemics were discharged from the Department of Infectious Disease at Blegdamshospitalet, Copenhagen, with a diagnosis of paralytic PM, and to age- and gender-matched controls without PM. Information about symptoms at the acute stage of disease was obtained from hospital records. Logistic regression analysis with adjustment for age and gender was applied to compare the occurrence of late symptoms in cases and controls and within the above-mentioned groups of individuals with a history of PM. Results: (i) Compared with controls, individuals with a history of polio significantly more often reported muscle symptoms, pain, neuropathic sensory symptoms, and bulbar symptoms; (ii) the occurrence of symptoms did not seem to be related to symptoms of the initial PM; and (iii) symptom prevalence was significantly higher in individuals with a history of polio who reported PPS as compared with those who did not. Conclusion: Our data indicate that individuals with a history of PM late in life experience a variety of symptoms that cannot be attributed to lesions of the anterior horn. Furthermore, late symptoms do not seem to be related to initial symptoms of the acute stage of PM but to reported PPS. The last finding supports the perception that the cause of PPS is not just normal ageing.

show abstract

Former poliomyelitis as a health and socioeconomic factor. A paired sibling study

Cited by 13 publications

References 21 publications

Post‐polio syndrome and total health status in a prospective hospital study

Post‐polio syndrome and total health status in a prospective hospital study

Post-Polio Syndrome and Risk Factors in Korean Polio Survivors: A Baseline Survey by Telephone Interview

Neurological Symptoms in Danes with a History of Poliomyelitis: Lifelong Follow-Up of Late Symptoms, their Association with Initial Symptoms of Polio, and Presence of Postpolio Syndrome

Contact Info

Product

Resources

About