Forming a stone in pelviureteric junction obstruction: cause or effect?

Stasinou, Theodora; Bourdoumis, Andreas; Masood, Junaid

doi:10.1590/s1677-5538.ibju.2015.0515

Cited by 22 publications

(15 citation statements)

References 39 publications

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“…[17] The incidence of kidney stone has been reported to be approximately 16-30%. [14,[18][19][20] In the present study, while flank pain was the primary symptom with 56.5%, 13% of the patients with UPJO were found incidentally. Of the 23 patients, 13 (56.5%) presented with crossing aberrant vessel and 4 (17.4%) with kidney stone.…”

Section: Discussionsupporting

confidence: 44%

Laparoscopic pyeloplasty in ureteropelvic junction obstruction: A single-center experience

Demirkol¹

2021

Laparosc Endosc Surg Sci

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Introduction:The aim of the study is to retrospectively evaluate the perioperative and post-operative outcomes of the initial laparoscopic pyeloplasties (LPs); we performed in our clinic in the treatment of ureteropelvic junction obstruction (UPJO). Materials and Methods:The data of 23 patients who underwent LP with the diagnosis of UPJO between February 2016 and March 2020 in our clinic were retrospectively analyzed. The charts of patients such as demographic data, presenting complaint, pre-operative imaging, operation time, presence of crossing aberrant vessel, post-operative complications, hemoglobin drop, length of drain and hospital stay, and success rates were evaluated. Results:The mean age of patients was 25.5±17.1 (4-63) years with a male predominance of 56.5%. Of the 23 patients, 22 had primary and one patient had secondary UPJO previously treated with retrograde endopyelotomy. The mean operative time, drain stay time, and hospital stay time were 214.8±43.1 (160-310) min, 2.8±1.0 (2-7) days, and 3.5±1.8 (2-9) days, respectively. Although no major operative or post-operative complications were seen in our series, 2 (8.7%) patients had minor operative complications and 4 (17.3%) patients had minor postoperative complications. The mean follow-up period of all patients followed for at least 3 months was 13.9±7.8 (3-34) and the surgical success rate was 95.7%. Conclusion:Due to increased worldwide experience in laparoscopic surgery, the challenge on intracorporeal suturing of LP in initial cases is overcome in a short time. With a high success rate, low post-operative complication rate, and low hospital stay, our initial series results are consistent with high-volume studies in the literature.

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Section: Discussionsupporting

confidence: 44%

Laparoscopic pyeloplasty in ureteropelvic junction obstruction: A single-center experience

Demirkol¹

2021

Laparosc Endosc Surg Sci

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“…Risk factors associated with infection stone formation include: female gender (usually a 2:1 ratio compared to males), which is associated with a high frequency of UTIs 15 ; age, given that infection stones seem to be most frequent in elderly patients 37 ; anatomical alterations of the urinary tract such as ureteropelvic junction stenosis 38 ; urinary diversion 39 and urinary stasis 40 as a result of…”

Section: Risk Factorsmentioning

confidence: 99%

Current insights into the mechanisms and management of infection stones

et al. 2018

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Infection stones are complex aggregates of crystals amalgamated in an organic matrix that are strictly associated with urinary tract infections. The management of patients who form infection stones is challenging owing to the complexity of the calculi and high recurrence rates. The formation of infection stones is a multifactorial process that can be driven by urine chemistry , the urine microenvironment, the presence of modulator substances in urine, associations with bacteria, and the development of biofilms. Despite decades of investigation, the mechanisms of infection stone formation are still poorly understood. A mechanistic understanding of the formation and growth of infection stones-including the role of organics in the stone matrix, microorganisms, and biofilms in stone formation and their effect on stone characteristics-and the medical implications of these insights might be crucial for the development of improved treatments. Tools and approaches used in various disciplines (for example, engineering, chemistry , mineralogy , and microbiology) can be applied to further understand the microorganism-mineral interactions that lead to infection stone formation. Thus, the use of integrated multidisciplinary approaches is imperative to improve the diagnosis, prevention, and treatment of infection stones.

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“…The most common cause of hydronephrosis is urinary tract obstruction. 4 Crystal accumulation in these patients can cause stone formation. In addition, the presence of kidney stones can be the cause of hydronephrosis.…”

Section: Discussionmentioning

confidence: 99%

Effects of severe hydronephrosis on the outcomes of percutaneous nephrolithotomy with one-shot dilation method

Miçooğulları¹,

Yücel²,

Sueluzgen³

et al. 2021

Urologia

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Objective: To investigate the effect of the presence of severe hydronephrosis on percutaneous nephrolithotomy (PNL) outcome in patients who underwent PNL operation with one-shot dilatation technique. Materials and methods: Medical data of 989 patients underwent PNL operation in our clinic between 2012 and 2018 were retrospectively reviewed. We included 373 of the patients underwent PNL operation due to renal pelvic stone, who were older than 18 years of age, who did not have any urinary tract abnormality, and had no previous history of open renal stone operation. Patients were divided into two groups according to the presence of severe hydronephrosis and absence of hydronephrosis. These two groups were compared in terms of age, gender, body mass index (BMI), number of stones, stone burden, operation duration, fluoroscopy time, hospitalization time, hemoglobin and creatinine change, complications, and stone free rate. Results: There was no statistically significant difference between the groups in terms of age, gender, BMI, stone number, stone size, stone density, operation duration, fluoroscopy time, and hospitalization duration. The mean change in hemoglobin was 1.5 g/dL in group 1 and 1.1 g/dL in group 2. This difference was statistically significant ( p = 0.006). Postoperative blood transfusion was required for 3 patients (2.1%) in group 1 and 12 patients (5.1%) in group 2. This difference was statistically significant ( p < 0.001). Conclusion: Only the presence of severe hydronephrosis was found to be associated with the change in hemoglobin and postoperative blood transfusion.

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Forming a stone in pelviureteric junction obstruction: cause or effect?

Cited by 22 publications

References 39 publications

Laparoscopic pyeloplasty in ureteropelvic junction obstruction: A single-center experience

Laparoscopic pyeloplasty in ureteropelvic junction obstruction: A single-center experience

Current insights into the mechanisms and management of infection stones

Effects of severe hydronephrosis on the outcomes of percutaneous nephrolithotomy with one-shot dilation method

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