Formulation and Evaluation of Antiaging Ointment Containing Microencapsulated Turmeric and Jojoba Oil

Abstract

Introduction: Skin health and beauty is essential for maintaining the overall well-being of human life. In the current fast-paced world, factors like busy schedules, unhealthy diets, and harsh environmental conditions can lead to noticeable signs of aging. Therefore, it is crucial to find effective solutions to address these concerns and maintain healthy, youthful-looking skin. To address this problem, we prepaid anti-aging ointment. And the beauty of the formulation is it contains microencapsulated turmeric and jojoba oil. Material and methods: Microcapsules were synthesized through the utilization of the ionic gelation method. In this method, sodium alginate is used as polymer and calcium chloride as cross-linker. These microcapsules were then incorporated into the ointment base to formulate the anti-aging ointment. Turmeric and jojoba oil were incorporated into the ointment to provide anti-aging benefits. Results: After the assessment of the microcapsules, it was determined that the prepared microcapsules fall within the range of 400 to 1000 μm. From FTIR spectra revealed successful microencapsulation of oil by sodium alginate. TGA analysis indicates that the prepared microcapsules exhibited thermal stability. The physical properties, spreadability, viscosity, and pH of the ointment were observed within the specified range. Formulation shows sustained release of turmeric oil 68.81% and jojoba oil 74.81% over 6 hours and DPPH assay shows with increase in concentration of oil the free radical scavenging activity also increases. Conclusion: The oils incorporation of microcapsules has significantly improved the antiaging properties of the ointment. The microencapsulation of these oils enables a sustained release of the active ingredients within the ointment formulation. The DPPH assay results confirm that the formulated ointment possesses robust antioxidant properties.