A cepa or onion is the most edible vegetable throughout the world. It also has diverse pharmacological properties. It is a fibrous perennial plant belonging to the Amaryllidaceae family. Onions contain vitamins such as folic acid and vitamin B6. It also contains minerals such as magnesium, calcium, potassium, and phosphorus. It shows diverse pharmacological properties such as anticancer, antidiabetic, antioxidant, anticoagulant, antihypertensive and antidepressant and neuroprotective effects. It is believed to be a carminative and shows beneficial effects on circulatory and respiratory systems as well as the immune system. Allium cepa finds its uses in cancer because of many stress conditions such as oxidative stress can be subsided by the Allium cepa extract and formulations. In this review, an attempt was made to formulate the medicated syrup of A. cepa. Four such formulations were made (F1, F2, F3, F4). The F4 formulation was optimized and was stable. The Formulation F4 can be adopted for preparation of A. cepa syrup on Industrial scale.