2013
DOI: 10.37285/ijpsn.2013.6.3.4
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Formulation and Evaluation of Solubility Enhanced Ciprofloxacin

Abstract: In the case of solubility limited absorption, creating supersaturation in the GI fluid is very critical as supersaturation may provide great improvement of oral absorption. The techniques to create the so-called supersaturation in the GI fluid include microemulsions, emulsions, liposomes, complexations, polymeric micelles, and conventional micelles. Ciprofloxacin was chosen because it is practically insoluble in water; hence its salt form is used commercially, which is soluble in water. The objective of the pr… Show more

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