Formulation and in vitro comparative evaluation of orodispersible tablets of Pantoprazole

Ds, Srinivasa; R, Narayana Charyulu; Ds, Satyanarayana; Srilakshmi, D

doi:10.5958/0974-360x.2015.00249.8

Cited by 2 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…95,96 Additionally, effervescent tablets have shown promise in oral hygiene and antimicrobial activity, owing to the progress of effervescent buccal and denture tablets. [97][98][99] These tablets are versatile and effective for delivering not only oral drugs but also herbal 100,101 and nutraceutical formulations. 102 Effervescent tablet formulations have also advanced in cosmeceuticals, such as pedicure, manicure, and bath bomb preparations.…”

Section: Advancements In Effervescent Technologymentioning

confidence: 99%

A Comprehensive Review on Effervescent Tablets

Vanhere,

Derle,

Khatale

et al. 2023

J. Drug Delivery Ther.

View full text Add to dashboard Cite

Effervescent tablets are becoming increasingly popular due to their ease of administration and rapid onset of action. They typically contain acidic materials and carbonates or bicarbonates that react quickly in the presence of water, releasing carbon dioxide and improving API solubility and flavour masking. However, effervescent tablets can be bulky, and the reaction rate is difficult to control due to water's catalytic effect. This article discusses the advantages and disadvantages of effervescent tablets, common effervescent reactions, active ingredients that can be formulated, and the preparation and manufacturing process. It also evaluates effervescent granules and tablets and explores the latest advancements in effervescent technology. Overall, effervescent tablets offer a promising option for drug delivery, and ongoing research will undoubtedly yield even more advanced formulations in the future. Keywords: Effervescent granules, Effervescent tablets, Hot melt granulation, Carbon dioxide content, Water activity

show abstract

Section: Advancements In Effervescent Technologymentioning

confidence: 99%

A Comprehensive Review on Effervescent Tablets

Vanhere,

Derle,

Khatale

et al. 2023

J. Drug Delivery Ther.

View full text Add to dashboard Cite

show abstract

Formulation and Evaluation of Chronomodulated Pulsatile Drug Delivery System for Nocturnal Hyperacidity

Kharwade

Nair

Masurkar

et al. 2022

RJPT

View full text Add to dashboard Cite

Introduction: Chronomodulated pulsatile drug delivery system is basically time-controlled drug delivery system in which the release of drug in the body is allowed to match with circadian rhythm with controlled lag time. Aim and Objective: The objective of this work was to develop and evaluate oral pulsatile tablet of Pantoprazole sodium for the treatment of nocturnal hyperacidity. Pulsatile drug delivery system for Pantoprazole sodium was formulated initially as a core tablet followed by press coated. Five different compositions of the core tablet were prepared by using cross carmellose super disintegrant. Base on drug content and dissolution time F5 formulation optimised and proceeds for press coating. Five different compositions of press coating were prepared and evaluated for in vitro drug release. Result: The formulation C4 achieved a maximum of 99.65% cumulative drug release over a period of 3hr. 30 min. Lag time for C4 formulation was found to be 2 hr. It means that the system was found to be satisfactory in terms of drug release after a lag time. Conclusion: Since the developed formulation when taken at bedtime, the tablet would be expected to release the drug at midnight which provides better control with the nocturnal hyperacidity.

show abstract

Formulation and in vitro comparative evaluation of orodispersible tablets of Pantoprazole

Cited by 2 publications

References 4 publications

A Comprehensive Review on Effervescent Tablets

A Comprehensive Review on Effervescent Tablets

Formulation and Evaluation of Chronomodulated Pulsatile Drug Delivery System for Nocturnal Hyperacidity

Contact Info

Product

Resources

About