Formulation ingredients for toothpastes and mouthwashes

Abstract

In order to achieve the multi-claim products required for the dental care category, it is necessary for the formulator to use a variety of different ingredients. This places a number of demands on the development process. Innovations in the areas of pharmaceutical technology have contributed to the formulation of the products having superior efficacy as well as other attributes that may contribute to clinical response and patient acceptability. Improved clinical efficacy and tolerability, along with conditioning signals, should encourage patient compliance with oral hygiene further complementing professional efforts directed at disease prevention. The most effective way of preventing the development of dental disease is in controlling the production of dental plaque. It is formed by microbial action. The removal of plaque from the teeth and related areas is essential for the maintenance of a healthy mouth. In this paper we have presented the main components of toothpastes and mouthwashes. For the active ingredients, their supposed effect as therapeutic agents is also explained.

Essential Oils of Lamiaceae Family Plants as Antifungals

“…Both essential oils from Lamiaceae plants and mono-substances are used in toothpastes and mouthwashes. In many of these the following chemicals, like limonene, linalool, menthol, and thymol, are presented as flavorings and fragrances [192,193]. Additionally, in some toothpastes are essential oils, e.g., in "Parodontax ® " occurs Salvia officinalis oil, Mentha piperita oil, and Mentha arvensis oil; in "Lacalut Active Herbal" is Mentha arvensis oil, Thymus vulgaris oil, and Salvia officinalis oil, while in "Signal Family Herbal Fresh" are oils from Mentha piperita and Salvia officinalis [194].…”

Mouthwash Use and Associated Factors among Saudi Adults: A Cross-sectional Study

“…They also function as remineralizing agents, antimicrobial, astringent, analgesic, buffering, deodorizing to neutralize odor, or oxygenating cleansing action. Cosmetic mouthwashes can be used as fresheners or to reduce staining when it is superficial in unattached biofilm [13,14].…”

Potential application of Bacillus subtilis SPB1 lipopeptides in toothpaste formulation

“…As abrasive agents, we used sodium carbonate [25] and calcium carbonate [26] . Glycerin, sodium fluoride and sodium alginate were used, respectively, as humectant, fluoride and binder agents [27] . The tested toothpastes were divided into three groups: the first one contained biosurfactant and was noted BIO, the second one contained sodium dodecyl sulfate and noted SDS and the third one, served as a control, did not contain emulsifier and was noted SS.…”