Formulation of Chlorpromazine Bio-Nano Gel Using Prunus Amygdalus Bio-Retardant for Brain Targeting via Nasal Route

Madhav, N. V. Satheesh; Raina, Deepika

doi:10.20530/ijta_31_5-9

Cited by 3 publications

(9 citation statements)

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“…The bionanosuspension can be prepared by a novel method called the sonication method [13]. In this method, the biopolymer as bio stabilizer cum bioretardant was mixed with other ingredients like a preservative, surface active agent like PVA, nanosizent with the distilled water to make a well-dispersed suspension [14]. Then the mixture was subjected to bath sonication for 10-15 cycles to formulate the nanosized drug-loaded bionanosuspension [4,15].…”

Section: Novel Sonication Methods For Nanoparticles Preparationmentioning

confidence: 99%

“…This can be evaluated by x-ray powder extraction, scanning electron microscopy (SEM) characterization, transmission electron microscopy (TEM) characterization. Differential Scanning Calorimetry (DSC) is also another method for characterizing crystallinity [6,14].…”

Section: Evaluation Parameters For Biopolymeric Nanoformulationsmentioning

confidence: 99%

“…So the conclusion was that the external acoustic route can be used as the promising route for drug targeting to brain in treatment of depression. [14], describes about formulation of chlorpromazine bio-nanogel by using the isolated biopolymer as bioretardant from Prunus amygdalus. The prepared bionanogel was evaluated for the delivery of chlorpromazine targeting to brain.…”

Section: Bionanoformulation In Drug Deliverymentioning

confidence: 99%

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Assessment of Mycological Quality of Groundwater in Yenagoa Metropolis, Bayelsa State, Nigeria

Richard¹,

Aseibai²

2021

SJMH

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This study examined the mycological quality of groundwater in Yenagoa metropolis, Bayelsa State, Nigeria. Triplicate water samples were obtained from 8 locations in the metropolis, and the fungi quality analyzed following standard microbiological procedures. Results showed that total fungi density ranged from 5.2±1.00 x102 to 8.50±0.56 x103 CFU/ml. Analysis of variance indicates statistical variation (p=0.001) across locations with total fungi density exceeding the limit of 102 CFU/ml specified by World Health Organization/Food and Agricultural Organization for potable water in 62.50% of samples. Eight fungi isolates (species) were identified in the study with frequency across the locations as follows: Aspergillus flavus (20.59%), Aspergillus fumigatus (20.59%), Aspergillus niger (20.59%), Cladosporum (5.88%), Fusarium (2.94%), Mucor (8.82%), Penicilium (14.71%) and Rhizopus (5.88%). Of these, Aspergillus species were predominant across the locations. Since groundwater meets diverse purposes, it is essential that it is suitable for the desired use, and this can be done using appropriate technology to make groundwater potable for human consumption.

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Section: Novel Sonication Methods For Nanoparticles Preparationmentioning

confidence: 99%

Section: Evaluation Parameters For Biopolymeric Nanoformulationsmentioning

confidence: 99%

Section: Bionanoformulation In Drug Deliverymentioning

confidence: 99%

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Assessment of Mycological Quality of Groundwater in Yenagoa Metropolis, Bayelsa State, Nigeria

Richard¹,

Aseibai²

2021

SJMH

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Section: Novel Sonication Methods For Nanoparticles Preparationmentioning

confidence: 99%

Section: Evaluation Parameters For Biopolymeric Nanoformulationsmentioning

confidence: 99%

Excess Weight Among Preschool Children in a Lower-Middle-Income Country: Predictors and Perspectives of Prevention

Fredj¹,

Ghammam²,

Zammit³

et al. 2021

SJMH

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Objective: We aimed to assess the weight status and to determine predicted factors of excess weight among Tunisian preschool children. Methods: We conducted a cross-sectional study among preschoolers attending kindergarten during 2016-2017 school-years in Sousse, Tunisia. The children’s parents completed the self-administered questionnaire. Anthropometric measures (Weight and height) were taken for the children. Weight status considered body mass index (BMI) and excess weight was defined by the International Obesity Task Force (IOTF) standards. Odds ratios for excess weight were calculated using binary logistic regression analyses. Results: A total of 364 preschoolers were included with a mean age 4.49±0.9 years. The ratio boys/girls was 1.05. The prevalence of excess weight was 31.3%; CI95%:[26.7%-36.5%]). Female gender (AOR=1.74; CI95%:[1.07-2.83]), working mother (AOR=1.75;CI95%:[1.04-2.92]), sedentary behavior (AOR=1.87;CI95%:[1.01-3.51]), eating sweets (AOR=1.95;CI95%:[1.19-3.19]), eating while watching television (AOR=2.53;CI95%:[1.23-5.18]) were positively associated with greater risk of excess weight while sleep duration<10h (AOR=0.41;CI95%:[0.24-0.71]) and less educated mother (AOR=0.35;CI95%:[0.12-0.96]) were negatively associated with excess weight. Conclusion: Our results show that the prevalence of overweight and obesity among preschoolers was alarming. Prevention of obesity should start early in life through a multisectoral approach.

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An Overview on Biopolymer: A Novelistic Bio-Excipient in Nanoparticulate Drug Delivery

Kumar¹,

Madhav²,

Verma³

et al. 2021

SJMH

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The point of this review is to feature the novelistic properties as bioexcipient, isolated from different regular natural sources like legumes, seeds, leaves, vegetables, bits, roots, barks and so on and to investigate the probability in medication conveyance framework. The biomaterial s have been exposed to different physicochemical assessments alongside unearthly examination including UV, FT-IR, Mass and 1H NMR. The confined biomaterial was discovered tom be polymeric in nature having a various utilitarian properties. Based on its inbuilt polymeric properties, the biomaterial secluded from various sources, can be utilized as an option in contrast to accessible standard polymers at extremely efficient economical scale. The separated biopolymer comprised of an interesting polymeric properties like accessible standard polymers. The isolated biomaterial from natural sources shown distinctive inbuilt polymeric properties by execution of various physico-substance examination. As we probably are aware there are various polymers accessible and oftentimes utilized design of novel medication. Yet, detached biomaterial from natural sources have demonstrated about their novelistic various properties like biodegradability, bioretardant, bioadhesive, filmability etc.

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Formulation of Chlorpromazine Bio-Nano Gel Using Prunus Amygdalus Bio-Retardant for Brain Targeting via Nasal Route

Cited by 3 publications

References 0 publications

Assessment of Mycological Quality of Groundwater in Yenagoa Metropolis, Bayelsa State, Nigeria

Assessment of Mycological Quality of Groundwater in Yenagoa Metropolis, Bayelsa State, Nigeria

Excess Weight Among Preschool Children in a Lower-Middle-Income Country: Predictors and Perspectives of Prevention

An Overview on Biopolymer: A Novelistic Bio-Excipient in Nanoparticulate Drug Delivery

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