Formulation of Saudi Propolis into Biodegradable Chitosan Chips for Vital Pulpotomy

Balata, Gihan F; Abdelhady, Mohamed; Mahmoud, Ghada M; Matar, Moustafa A.; El-Latif, Amani N Abd

doi:10.2174/1567201814666170125121735

Cited by 15 publications

(32 citation statements)

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“…Biodegradable chitosan chips containing propolis was used in the treatment of vital pulpotomy [158]. The study of Balata et al compared the effect of propolis polyphenols (caffeic acid, quercetin, rutin, and chrysin) and formocresol (the gold standard dressing agent in pulpotomy) in the inflammatory response and hard tissue formation.…”

Section: Anti-inflammatory and Antioxidant Activitymentioning

confidence: 99%

Polyphenols in Dental Applications

2020

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(1) Background: polyphenols are a broad class of molecules extracted from plants and have a large repertoire of biological activities. Biomimetic inspiration from the effects of tea or red wine on the surface of cups or glass lead to the emergence of versatile surface chemistry with polyphenols. Owing to their hydrogen bonding abilities, coordination chemistry with metallic cations and redox properties, polyphenols are able to interact, covalently or not, with a large repertoire of chemical moieties, and can hence be used to modify the surface chemistry of almost all classes of materials. (2) Methods: the use of polyphenols to modify the surface properties of dental materials, mostly enamel and dentin, to afford them with better adhesion to resins and improved biological properties, such as antimicrobial activity, started more than 20 years ago, but no general overview has been written to our knowledge. (3) Results: the present review is aimed to show that molecules from all the major classes of polyphenolics allow for low coast improvements of dental materials and engineering of dental tissues.

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Section: Anti-inflammatory and Antioxidant Activitymentioning

confidence: 99%

Polyphenols in Dental Applications

2020

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“…61 Balata ve ark. 62 2017 yılında çözünebilir kitosan içerisine propolis ilave ederek yaptıkları pulpotomi tedavilerinde formokre-7tepeklinik zole kıyasla daha az pulpal inflamasyon olduğunu belirtmişler ve kitosan içeren tüm örneklerde sert doku oluşumu sağladığını vurgulamışlardır.…”

Section: Ankaferd Blood Stopperunclassified

Hemostatic agents for pulpotomy treatment in primary teeth

Delikan¹

2018

Yeditepe J Dent

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Süt dişlerindeki mine ve dentin kalınlığının daimi dişlere göre daha az olması, pulpa odasının daimi dişlere göre göreceli olarak daha geniş olması ve süt dişlerinde pulpa boynuzlarının yüzeye daha yakın olması sebebi ile pulpal tedavi gereksinimi daimi dişlere göre daha fazla görülmektedir. Çocuk diş hekimliğinde pulpotomi tedavisi sıklıkla kullanılan bir yöntemdir ve tedavinin başarısında kullanılan materyal önemli faktörlerden biridir. Pıhtı formasyonu iyileşmeyi olumsuz etkilediği gibi bakteriler için uygun bir ortam oluşturup bölgede enflamasyon ve enfeksiyonu tetikleyebilmekte, ayrıca pulpa dokusu ile üzerine konulan medikamentin temasını engellediği için tedavi başarısını düşürmektedir. Bu yüzden pulpotomi tedavisinde kalan pulpa dokusunda pıhtıyı ortadan kaldıran etkili bir hemostazın tedavinin başarısını artırıcı bir rol oynadığı düşünülmektedir. Bu nedenlerden dolayı hemostatik ajanlar pulpotomi tedavilerinde kullanılmaya başlanmıştır. Bu makalede, çocuk diş hekimliği pratiğinde pulpotomi tedavilerinde kullanılan farklı hemostatik ajanların derlenmesi amaçlanmıştır. Anahtar kelimeler: Çocuk diş hekimliği, pulpotomi, hemostatik ajanlar SUMMARY The need for pulpal treatment in the primary teeth is greater than the permanent teeth, because in primary teeth enamel and dentin is thinner, the pulp chamber is relatively wider and pulp horns are closer to the surface than permanent teeth. Pulpotomy is a frequently used method in pediatric dentistry and for the success of the treatment material is an important factor. Clot formation affects healing as well as it can create a favorable environment for the bacteria to induce inflammation and infection and also decreases the success of the treatment by preventing the pulp tissue-medicament contact. Therefore, it is believed that an effective haemostasis, increases treatment success. For these reasons hemostatic agents have begun to be used in pulpotomy treatments. The purpose of this paper is to review various hemostatic agents used in pulpotomy treatment in pediatric dentistry practice.

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“…Recent studies point out that biochemical and biophysical characteristics of polymers and membranes have great potential for application in different dentistry fields [24][25][26]. Due the biochemical properties of chitosan and the ability to interact and stimulate pulp cells, chitosan has been exploited in association with other materials to produce new bioactive pulp dressings [23,27].…”

Section: Introductionmentioning

confidence: 99%

Pulp repair response after the use of a dentin-pulp biostimulation membrane (BBio) in primary teeth: study protocol for a randomized clinical trial

Machado

Stafuzza

Vitor

et al. 2020

Trials

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Background Vital pulp therapy aims at maintaining the pulp tissue injured but vital. Thus, the use of capping materials that induce tissue regeneration is a great current trend. This study aims to evaluate clinically and radiographically the pulp repair after the use of dentin-pulp biostimulation membrane in primary teeth. Methods Four hundred and sixty-eight teeth from children aged between 5 and 9 years old, both genders, with deep caries lesion with pulp involvement, but no furcal impairment and any sign of necrosis will be selected. The vital pulp therapy will be performed with mineral trioxide aggregate (control group) and dentin-pulp biostimulation chitosan membrane (BBio group). The clinical and radiographic outcomes will be assessed at 12 and 24 months after treatment. The thickness of the dentin barrier will be verified through Image J2 software. The Wilcoxon signed rank test and Mann-Whitney test will respectively compare the intra- and intergroup clinical and radiographic outcomes. Paired t test and independent t test will respectively compare the intra- and intergroup radiographic measurements. The logistic regression will be applied, and the degrees of this association will be measured using odds ratio (OR) and 95% confidence interval (95% CI). Discussion Therefore, this study protocol aims at new perspectives of vital pulp therapy of primary teeth by employing new easy-handling, low-cost material to keep viable the pulp tissue capable of regenerating and maintain the physiological process of deciduous tooth exfoliation. Trial registration Brazilian Registry of Clinical Trials RBR-6vr58b. Registered on 17 February 2019.

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Formulation of Saudi Propolis into Biodegradable Chitosan Chips for Vital Pulpotomy

Abstract: Formulation of commercial Saudi propolis as a biodegradable chitosan chip is an effective alternative to the commercially available chemical agents for the treatment of vital pulpotomy.

Cited by 15 publications

References 0 publications

Polyphenols in Dental Applications

Polyphenols in Dental Applications

Hemostatic agents for pulpotomy treatment in primary teeth

Pulp repair response after the use of a dentin-pulp biostimulation membrane (BBio) in primary teeth: study protocol for a randomized clinical trial

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