Formulation Optimization, Rheological Characterization and Suitability Studies of Polyglucoside-based Azadirachta indica A. Juss Emollient Cream as a Dermal Base for Sun Protection Application

Banerjee, Kaushita; Thiagarajan, N.; Thiagarajan, Padma

doi:10.4172/pharmaceutical-sciences.1000308

Cited by 7 publications

(5 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cluster analysis indicated that the PAs (except CA) changed the fungi structure compared to CCG and NFS treatments, and these treatments behaved similarly on fungi community. We speculate the cinnamic acid is not the major PA accumulating from consecutive ginseng monoculturing (Banerjee et al, 2017, Kuscu et al, 2017, Messina et al, 2017, Singh et al, 2017).…”

Section: Discussionmentioning

confidence: 87%

“…In recent years, ginseng was mainly dependent on artificial cultivation in China. But this method of cultivation was severely aggravated by continuous cropping obstacles, including Cylindrocarpon root rot caused by Cylindrocarpon destructans (Zinns) Scholten, which is the most severe soil-borne disease and is difficult to control in ginseng fields (Akin et al, 2017, Banerjee et al, 2017, Demir et al, 2017, Khan et al, 2018a, Khan et al, 2018b). This disease becomes more serious after continuous cropping and the symptoms can be observed at all developmental stages of the plant (Rahman and Punja-Z, 2005, Yan and Fu, 2002) and results in significant yield decline at last (Dou et al, 1996).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of phenolic acids from ginseng rhizosphere on soil fungi structure, richness and diversity in consecutive monoculturing of ginseng

Zhou

et al. 2018

Saudi Journal of Biological Sciences

View full text Add to dashboard Cite

Ginseng yield and quality are seriously compromised by consecutive monoculturing in northeastern China. The imbalance of soil fungi communities and autotoxicity of ginseng are the major factors in consecutive monoculturing ginseng crops. Soil fungal communities were identified using Illumina MiSeq sequencing, applied to soils that consecutively cultured ginseng (CCG) for six years and new forest soil (NFS), or receiving application of phenolic acids (PAs). The CCG field received five treatments with five different phenolic acids, including gallic acid (GA), salicylic acid (SA), 3-phenylpropionic acid (3-PA), benzoic acid (BA) and cinnamic acid (CA), which were detected from ginseng rhizosphere in consecutive cropping soil. Fungal richness, fungi diversity, community composition, relative taxon abundances, root rot disease, and growth rate were compared among the different treatments. 579 fungal operational taxonomic units at 97% ITS sequence identity were found among 201,617 sequence reads derived from 18 separate soil samples. Members of the phylum Ascomycota dominated the soil fungal communities, and putative pathogens, such as Fusarium, Gibberella and Nectriaceae_unclassified which may include the abundant sexual morph of Cylindrocarpon destructans, showed higher relative abundances in the CCG fields. Compared to the CCG and NFS fields, PAs (except CA) enhanced the fungi richness and decreased fungi diversity. Cluster analysis indicated that the PAs (except CA) changed the fungi structure in a uniform way. PAs stimulate root rot disease and enhance disease severity, restricting plant growth. The results suggest that the PAs (except CA) may enhance the fungi richness, decrease the fungi diversity and changed the fungi structure to increase fungal pathogen loads, which could explain the declined yield and quality of ginseng in consecutively monocultured ginseng crops.

show abstract

Section: Discussionmentioning

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Effects of phenolic acids from ginseng rhizosphere on soil fungi structure, richness and diversity in consecutive monoculturing of ginseng

Zhou

et al. 2018

Saudi Journal of Biological Sciences

View full text Add to dashboard Cite

show abstract

“…Such Neem formulation had no cytotoxicity in 3T3 cell lines, as well as no damage to the natural cutaneous flora. In addition to this, when titanium dioxide was added to this cream, it showed greater photoprotective activity than the commercial product [7].…”

Section: In Vivo Tests (Subjects) For Cosmetic Applicationsmentioning

confidence: 90%

“…The SPF values were higher than the commercial cream, thus, revealing this plant as an alternative for the production of multifunctional sunscreens. Moreover, such cream was inoffensive to representative skin flora [7]. Likewise, until the present date, there have been only a few efforts of in vivo testing with cosmetic samples containing A. indica ethanolic extract with satisfactory safety results [8].…”

Section: Introductionmentioning

confidence: 99%

Azadirachta indica (Neem) as a Potential Natural Active for Dermocosmetic and Topical Products: A Narrative Review

et al. 2022

View full text Add to dashboard Cite

Azadirachta indica (Neem) is a large tree that is native to India and is traditionally used due to its several properties, mainly to treat skin diseases, as well as its “herbicidal” activity. Its bark, leaves, seeds, fruits and flowers are widely used in medicinal treatment due to the presence of active secondary metabolites with biological effects, mainly limonoids and tetranortriterpenoids, such as azadirachtin. Thus, A. indica was studied in a variety of conditions, such as anticancer, antiseptic, anti-inflammatory and chemopreventive agents, as well as a biopesticide. Furthermore, differentiated cell tissue in A. indica cultivation was reported to produce active metabolites for different purposes. However, only a few studies have been developed regarding its potential use in cosmetics. For instance, most studies explained the antimicrobial properties in health conditions, such as acne, dandruff and personal health care. Here, we summarized not only the most common cosmetic claims to treat acne but also mitigating other skin disorders related to inflammatory and oxidant processes in recent in vivo studies and patents to aid researchers and industrialists to select A. indica derivatives as novel cosmetic ingredients.

show abstract

“…It is important to properly implement the prevention, diagnosis and treatment of ischemic stroke in young adults (Arik et al, 2017, Kevrekidis et al, 2018). It has been confirmed that IS was a result of multiple factors, such as chronic diseases, inflammation, and genetic variants (Banerjee et al, 2017). Genetic factors play a key predisposing role of IS in family and twin studies (Murray and Lopez, 2013).…”

Section: Introductionmentioning

confidence: 97%

Association between PDE4D polymorphism and ischemic stroke in young population

Yue

Liu

Yan

et al. 2019

Saudi Journal of Biological Sciences

View full text Add to dashboard Cite

Objective To explore the association between the polymorphisms of the phosphodiesterase (PDE) 4D gene (SNP83 and SNP87) and the risk of ischemic stroke (IS) in Chinese young population. Methods This study included 393 patients who were divided into IS group and non-IS group. Semiconductor high-throughput sequencing technology and multivariate logistic regression analysis were performed. Results In the case group, the frequency of CC genotype and C allele of the SNP83 gene was significantly higher than that in the control group. There was no significant difference in genotype frequency distribution of SNP87 between the two groups. Conclusion We found an association between SNP83 and the risk of IS in Chinese young population from northern Henan province. There was not a significant association between SNP87 and IS in Chinese young population.

show abstract

Formulation Optimization, Rheological Characterization and Suitability Studies of Polyglucoside-based Azadirachta indica A. Juss Emollient Cream as a Dermal Base for Sun Protection Application

Cited by 7 publications

References 24 publications

Effects of phenolic acids from ginseng rhizosphere on soil fungi structure, richness and diversity in consecutive monoculturing of ginseng

Effects of phenolic acids from ginseng rhizosphere on soil fungi structure, richness and diversity in consecutive monoculturing of ginseng

Azadirachta indica (Neem) as a Potential Natural Active for Dermocosmetic and Topical Products: A Narrative Review

Association between PDE4D polymorphism and ischemic stroke in young population

Contact Info

Product

Resources

About