Fortuitous diagnosis of monkeypox in a patient hospitalized for several days: risk assessment and follow-up for exposed healthcare workers

Phelippeau, Michael; Loison, Geoffrey; Rucay, Pierre; Guillou‐Guillemette, Hélène Le; Ndiaye, Diama; Dubée, Vincent; Legeay, Clément

doi:10.1016/j.jhin.2022.11.002

Cited by 2 publications

(10 citation statements)

References 4 publications

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“…This systematic review included 15 studies [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ] ( Table 1 ): seven studies were from Africa [ 18 , 19 , 20 , 21 , 23 , 24 , 25 ], six of which from Zaire, now called Democratic Republic of the Congo [ 18 , 19 , 20 , 21 , 24 ], three studies from the USA [ 22 , 29 , 30 ], one from Singapore [ 26 ], and three studies from Europe, one from United Kingdom [ 27 ] and two from Spain [ 28 , 32 ], respectively. One study had no reference to the country of origin [ 31 ]. Ten studies were published before 2022 [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ], and the remaining five were published in 2022 or 2023 [ 28 , 29 , 30 , ...…”

Section: Resultsmentioning

confidence: 99%

“…One study had no reference to the country of origin [ 31 ]. Ten studies were published before 2022 [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ], and the remaining five were published in 2022 or 2023 [ 28 , 29 , 30 , 31 , 32 ].…”

Section: Resultsmentioning

confidence: 99%

“…In two studies, the outcome assessment was only clinical [ 26 , 27 ]. Another study does not specify how the outcome was assessed [ 31 ]. The other 12 had, at some point, confirmation by serological findings or virus isolation [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 28 , 29 , 30 ].…”

Section: Resultsmentioning

confidence: 99%

“…A total of 7319 contacts were surveyed, and 273 of them were considered Mpox positive cases. Seven studies reported household contact [ 18 , 19 , 20 , 21 , 23 , 24 , 28 ], six studies reported surface/fomites contact [ 22 , 26 , 28 , 30 , 31 , 32 ], two of them at a tattoo studio [ 28 , 32 ], two studies reported potential contact with airway particles [ 22 , 30 ] and three reported skin-to-skin contact [ 22 , 30 , 31 ], two studies reported intrafamilial contact [ 23 , 25 ], one study reported sexual contact [ 28 ], one study reported direct contact with the patient or the patient’s surroundings or specimens [ 26 ], and one study reported person-to-person but no sexual or skin-to-skin contact [ 29 ]. Two studies focused on Mpox transmission on pediatric population [ 23 , 28 ].…”

Section: Resultsmentioning

confidence: 99%

“…Drinking from the same cup, eating from the same dish, sleeping in the same room, and sleeping in the same bed were positively associated with transmission [ 24 ]. Five studies showed no evidence of transmission [ 22 , 26 , 29 , 30 , 31 ] despite contact with surfaces, skin-to-skin contact, or through airway particles in five healthcare centers [ 22 , 26 , 27 , 30 , 31 ] and one in a prison facility [ 29 ].…”

Section: Resultsmentioning

confidence: 99%

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Mpox Person-to-Person Transmission—Where Have We Got So Far? A Systematic Review

Pinto

Costa

Gonçalves

et al. 2023

Viruses

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The recent multi-country outbreak of Mpox (Monkeypox disease) constituted a public health emergency. Although animal-to-human transmission is known to be the primary way of transmission, an increasing number of cases transmitted by person-to-person contact have been reported. During the recent Mpox outbreak sexual or intimate contact has been considered the most important way of transmission. However, other routes of transmission must not be ignored. The knowledge of how the Monkeypox Virus (MPXV) spreads is crucial to implement adequate measures to contain the spread of the disease. Therefore, this systematic review aimed to collect scientific data published concerning other implicated sources of infection beyond sexual interaction, such as the involvement of respiratory particles, contact with contaminated surfaces and skin-to-skin contact. The current study was performed using the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Publications analyzing contacts of Mpox index cases and their outcome after contact were included. A total of 7319 person-to-person contacts were surveyed and 273 of them became positive cases. Positive secondary transmission of MPXV was verified after contact with people cohabiting in the same household, with family members, with healthcare workers, or within healthcare facilities, and sexual contact or contact with contaminated surfaces. Using the same cup, sharing the same dishes, and sleeping in the same room or bed were also positively associated with transmission. Five studies showed no evidence of transmission despite contact with surfaces, skin-to-skin contact, or through airway particles within healthcare facilities where containment measures were taken. These records support the case for person-to-person transmission and suggest that other types of contact beyond sexual contact pose a significant risk of acquiring the infection. Further investigation is crucial to elucidate MPXV transmission dynamics, and to implement adequate measures to contain the spread of the infection.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Mpox Person-to-Person Transmission—Where Have We Got So Far? A Systematic Review

Pinto

Costa

Gonçalves

et al. 2023

Viruses

View full text Add to dashboard Cite

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Mpox exposure and transmission in healthcare settings during the 2022 global outbreak

Zachary

Philpotts

Shenoy

2023

Current Opinion in Infectious Diseases

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Purpose of review The risk of nosocomial transmission of mpox during the 2022 global outbreak is not well described. We evaluated reports of exposures to healthcare personnel (HCP) and patients in healthcare settings and risk of transmission. Recent findings Reported nosocomial transmission of mpox has been rare and associated primarily with sharps injuries and breaches in transmission-based precautions. Summary Currently recommended infection control practices, including the use of standard and transmission-based precautions in the care of patients with known or suspected mpox are highly effective. Diagnostic sampling should not involve the use of needles or other sharp instruments.

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Fortuitous diagnosis of monkeypox in a patient hospitalized for several days: risk assessment and follow-up for exposed healthcare workers

Cited by 2 publications

References 4 publications

Mpox Person-to-Person Transmission—Where Have We Got So Far? A Systematic Review

Mpox Person-to-Person Transmission—Where Have We Got So Far? A Systematic Review

Mpox exposure and transmission in healthcare settings during the 2022 global outbreak

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