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doi:10.1177/00912709922007895

The Journal of Clinical Pharma

1999

DOI: 10.1177/00912709922007895

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Cited by 3 publications

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Accuracy of self-report, biological tests, collateral reports and clinician ratings in identifying substance use disorders among adults with schizophrenia.

Desmarais

Dorn

Sellers

et al. 2013

Psychology of Addictive Behaviors

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Identifying substance use disorders among adults with schizophrenia presents unique challenges, but is critical to research and practice. This study examined: a) the accuracy of assessments completed using various approaches in identifying substance use disorders; b) their ability to discriminate between disorders of abuse and dependence; and c) the benefits of using multiple indicators to identify substance use disorders. Data are from the Clinical Antipsychotic Trials of Intervention Effectiveness study. The sample comprised 1,460 community-based adults with schizophrenia, 15.8% (n = 230) of whom were positive for a current (past month) drug or alcohol use disorder using the Structured Clinical Interview for DSM-IV Disorders (SCID). Clinician ratings, self-report, collateral reports, and results of hair and urine tests were compared to SCID diagnoses. Congruence with SCID diagnoses was good across approaches and evidence for superiority of one approach over another was limited. No approach discriminated between abuse and dependence. There was limited benefit of using multiple indicators. Findings suggest that the decision regarding the ‘best’ approach for identifying substance use disorders among adults with schizophrenia may be made through consideration of practical issues and assessment purpose, rather than selection of the approach that yields the most accurate diagnostic assessment.

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Accuracy of self-report, biological tests, collateral reports and clinician ratings in identifying substance use disorders among adults with schizophrenia.

Desmarais

Dorn

Sellers

et al. 2013

Psychology of Addictive Behaviors

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Evaluation of a New Phencyclidine Enzyme Immunoassay for the Detection of Phencyclidine in Urine with Confirmation by High-Performance Liquid Chromatography-Tandem Mass Spectrometry

Poklis¹,

Guckert²,

Wolf³

et al. 2011

Journal of Analytical Toxicology

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Influence of zinc and some commercial products on tramadol and apetryl detection in human urine samples

Elkhateeb

Arafa

2019

The Egyptian Journal of Forensic Sciences and Applied Toxicolog

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Urine drug testing plays an important role in detecting licit and illicit drug use. Adulteration of urine samples have been employed to disrupt these drug tests. Recently, zinc sulfate was used as an effective adulterant to bypass drug testing. Aim of the work: The aim of the current study was to evaluate the effect of zinc sulfate and some adulteration methods on detection of tramadol and apetryl in urine and their effects on the validity tests. Method: Tramadol and apetryl were added to urine sample that were obtained from a healthy, drug-free subject to yield samples of urine containing tramadol and apetryl with concentrations (200 ng/ ml & 400 ng/ ml). Visine eye drop, zinc sulfate and lemon were added to these samples as well as dilution was done. These samples were tested for their ability to generate false negative results for the immunoassay test screen. Results: All adulterated urine samples as regard both drugs generated false negatives results. PH paper test showed more acidic PH with lemon juice while visine, zinc sulfate and dilution gave light green coloration indicating slightly acidic PH. Specific gravity showed increase of specific gravity for urine adulterated with lemon but decrease in diluted urine. Conclusion: There are needs to a more effective and efficient approach to urinalysis due to the false negatives that can result from adulteration of urine samples.

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Cited by 3 publications

References 12 publications

Accuracy of self-report, biological tests, collateral reports and clinician ratings in identifying substance use disorders among adults with schizophrenia.

Accuracy of self-report, biological tests, collateral reports and clinician ratings in identifying substance use disorders among adults with schizophrenia.

Evaluation of a New Phencyclidine Enzyme Immunoassay for the Detection of Phencyclidine in Urine with Confirmation by High-Performance Liquid Chromatography-Tandem Mass Spectrometry

Influence of zinc and some commercial products on tramadol and apetryl detection in human urine samples

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