“…While their importance has been highlighted in the literature, and is likely to only increase (Colombo et al, 2011), there are still important issues which remain unresolved. Firstly, the qualitative and analytical models using market failure theory to justify STI policy are potentially limited when the innovation in question are related to transformational shifts and grand challenges (Nelson, 1994;Mazzucato, 2013a), and secondly, solid quantitative and empirical models to support the design of policies promoting technological breakthrough innovation are still scarce (Vilkkumaa et al, 2015).…”