2018
DOI: 10.1136/oemed-2017-104806
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Four decades of pulmonary tuberculosis in deceased South African miners: trends and determinants

Abstract: Changes in PTB time trends and determinants reflect the complex social and political environment in which mining occurs. Silica dust reduction remains a key intervention for tuberculosis reduction, together with tuberculosis and HIV treatment and management. The autopsy data provide reliable information to monitor progress towards the achievement of industry and national targets to reduce tuberculosis.

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Cited by 35 publications
(9 citation statements)
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“…This association between mining and respiratory disease is well described in a range of national and international literature. [13,[26][27][28][29]. Women and male miners appear to be protected from endocrine and metabolic diseases and circulatory system deaths compared to women and men manufacturing laborers and all women and all men.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…This association between mining and respiratory disease is well described in a range of national and international literature. [13,[26][27][28][29]. Women and male miners appear to be protected from endocrine and metabolic diseases and circulatory system deaths compared to women and men manufacturing laborers and all women and all men.…”
Section: Discussionmentioning
confidence: 99%
“…Further, in the USA, fatal injury rates in mining were found to be four times higher than the average for all industries [7]. In South Africa, studies reported miners to be at increased risk of Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) [8,9], respiratory diseases [10][11][12][13], and injuries [14][15][16]. In a 2008 mortality cohort study of platinum miners in South Africa, external causes were found to be the second most common cause of death after HIV [15].…”
Section: Introductionmentioning
confidence: 99%
“…The new study is notable for the robust persistence of the association between the odds of silicosis and tuberculosis at autopsy through the three time periods examined 5. When silicosis status is omitted from the models, the association of duration of employment in gold mining, a proxy of cumulative silica dust exposure, is more clearly seen.…”
mentioning
confidence: 86%
“…Occupational exposure to respirable crystalline silica (RCS) is an age-old problem. RCS is a confirmed human carcinogen ( 1 ), and exposure is also associated with non-malignant diseases such as silicosis ( 2 ) and tuberculosis ( 3 ). Interest in silica has been re-kindled in recent years, perhaps due to novel disease clusters in industries such as mining ( 4 ), and emerging hazards such as RCS-containing manufactured stone counter tops ( 5 ) and fracking ( 6 ) as well as by the recent IARC monograph, and revisions that lowered occupational exposure limits for RCS (e.g., 0.05 mg/m 3 in OSHA and European Union, 0.025 mg/m 3 for ACGIH TLV®).…”
Section: Introductionmentioning
confidence: 99%
“…RCS is a confirmed human carcinogen (1), and exposure is also associated with non-malignant diseases such as silicosis (2) and tuberculosis (3). Interest in silica has been re-kindled in recent years, perhaps due to novel disease clusters in industries such as mining (4), and emerging hazards such as RCS-containing manufactured stone counter tops (5) and fracking (6) as well as by the recent IARC monograph, and revisions that lowered occupational exposure limits for RCS (e.g., 0.05 mg/m 3 in OSHA and European Union, 0.025 mg/m 3 for ACGIH TLV R ). In a time of generally increasing concern about occupational disease, recent studies of the burden of occupational cancer have more precisely quantified the incidence of occupational disease associated with RCS exposure (7).…”
Section: Introductionmentioning
confidence: 99%