“…Based on the observation and analysis of the optimal segmentation thresholds and the segmentation results, it is further demonstrated that CLACO-MIS can obtain better segmentation results and verified that CLACO-MIS has good adaptability to different threshold levels. As exploration and exploration of the method exposes, the experts can also utilize the proposed ACO-based optimizer to tackle multi-faced feature spaces in other families of problems such as works in [ [107] , [108] , [109] ]. For future work, since CLACO is a superior swarm intelligence optimization algorithm, we will consider applying it to more fields, such as face recognition and micro-expression recognition [ 110 , 111 ], 3D deformable shape analysis [ 112 , 113 ], micro-expression spotting [ 111 , 114 ], service ecosystem [ 115 , 116 ], Lunar impact crater identification and age estimation [ 117 ], large scale network analysis [ 118 ], energy storage planning and scheduling [ 119 ], medical diagnosis [ [120] , [121] , [122] ], and prediction of brain-behavior [ 123 , 124 ].…”