Four hygienic-dietary recommendations as add-on treatment in depression

Garcı́a-Toro, Mauro; Ibarra, Olga; Gili, Margalida; Serrano, M. J.; Oliván, Bárbara; Vicens, Enric; Roca, Miquel

doi:10.1016/j.jad.2012.03.031

Cited by 49 publications

(58 citation statements)

References 19 publications

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“…Basic interventions comprising attention towards one cause and/or one biochemical mechanism (e.g., targeting a single neurotransmitter disturbance) makes the goal of remission or recovery less likely. This was highlighted in a recent study where giving simple written recommendations about lifestyle changes for sleep hygiene, physical activity, diet, and sunlight exposure enhanced outcomes to standard antidepressant treatment (Garcia-Toro et al, 2012). Remission/response rates reached 60% in the combined treatment group compared with only 10% in the anti-depressant only group.…”

Section: <<mentioning

confidence: 99%

A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise

Lopresti

Hood

Drummond

2013

Journal of Affective Disorders

532

412

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Research on major depression has confirmed that it is caused by an array of biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that play a significant mediating role in the development, progression and treatment of this condition. This review summarises animal and human-based studies on the relationship between these three lifestyle factors and major depressive disorder, and their influence on dysregulated pathways associated with depression, namely neurotransmitter processes, immuno-inflammatory pathways, hypothalamic-pituitary-adrenal (HPA) axis disturbances, oxidative stress and antioxidant defence systems, neuroprogression, and mitochondrial disturbances. Increased attention in future clinical studies on the influence of diet, sleep and exercise on major depressive disorder and investigations of their effect on physiological processes will help to expand our understanding and treatment of major depressive disorder. Mental health interventions, taking into account the bidirectional relationship between these lifestyle factors and major depression are also likely to enhance the efficacy of interventions associated with this disorder.

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Section: <<mentioning

confidence: 99%

A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise

Lopresti

Hood

Drummond

2013

Journal of Affective Disorders

532

412

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“…To date, to our knowledge only one RCT has examined the effects of combining multiple lifestyle adjustments for the treatment of depression. Garcia-Toro and colleagues [160] conducted an RCT of 80 outpatients with diagnosed major depressive disorder (non-SAD) who were taking antidepressant treatment. Four specific lifestyle recommendations consisting of dietary modification, exercise, sunlight exposure and sleep patterns were prescribed in the active group, while the control group was given instruction to perform a pattern of eating, sleeping, exercise and exposure to light which they considered might make them feel better.…”

Section: Reviewmentioning

confidence: 99%

Lifestyle medicine for depression

et al. 2014

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The prevalence of depression appears to have increased over the past three decades. While this may be an artefact of diagnostic practices, it is likely that there are factors about modernity that are contributing to this rise. There is now compelling evidence that a range of lifestyle factors are involved in the pathogenesis of depression. Many of these factors can potentially be modified, yet they receive little consideration in the contemporary treatment of depression, where medication and psychological intervention remain the first line treatments. “Lifestyle Medicine” provides a nexus between public health promotion and clinical treatments, involving the application of environmental, behavioural, and psychological principles to enhance physical and mental wellbeing. This may also provide opportunities for general health promotion and potential prevention of depression. In this paper we provide a narrative discussion of the major components of Lifestyle Medicine, consisting of the evidence-based adoption of physical activity or exercise, dietary modification, adequate relaxation/sleep and social interaction, use of mindfulness-based meditation techniques, and the reduction of recreational substances such as nicotine, drugs, and alcohol. We also discuss other potential lifestyle factors that have a more nascent evidence base, such as environmental issues (e.g. urbanisation, and exposure to air, water, noise, and chemical pollution), and the increasing human interface with technology. Clinical considerations are also outlined. While data supports that some of these individual elements are modifiers of overall mental health, and in many cases depression, rigorous research needs to address the long-term application of Lifestyle Medicine for depression prevention and management. Critically, studies exploring lifestyle modification involving multiple lifestyle elements are needed. While the judicious use of medication and psychological techniques are still advocated, due to the complexity of human illness/wellbeing, the emerging evidence encourages a more integrative approach for depression, and an acknowledgment that lifestyle modification should be a routine part of treatment and preventative efforts.

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“…health coach with no formal training (n 1); or an 'experimenter' (n 1). Only one study used written recommendations only and did not report on the qualifications of the individual who developed the guidelines (15) . (☺) Improvement in the anxiety score on the HADS in the intervention groups; mean value fell from 12 (SD 1·8) to 8·3 (SD 2·7) in G3 (a 30 % improvement, P < 0·001) and from 12·34 (SD 1·67) to 9·92 (SD 3·4) in G2 (a 19 % improvement, P < 0·001).…”

Section: Intervention Style and Programme Componentsmentioning

confidence: 99%

“…The magnitude of effect, among the positive studies reporting the requisite data, ranged from 0·19 to 2·02 (Cohen's d) (13,(15)(16)(17)25) . The remaining nine studies reported no intervention effects.…”

Section: Depressionmentioning

confidence: 99%

The impact of whole-of-diet interventions on depression and anxiety: a systematic review of randomised controlled trials

Opie

O’Neil²,

Itsiopoulos³

et al. 2015

Public Health Nutr.

197

145

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Although there was a high level of heterogeneity, we found some evidence for dietary interventions improving depression outcomes. However, as only one trial specifically investigated the impact of a dietary intervention in individuals with clinical depression, appropriately powered trials that examine the effects of dietary improvement on mental health outcomes in those with clinical disorders are required.

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Four hygienic-dietary recommendations as add-on treatment in depression

Cited by 49 publications

References 19 publications

A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise

A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise

Lifestyle medicine for depression

The impact of whole-of-diet interventions on depression and anxiety: a systematic review of randomised controlled trials

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