Four-Layered Sensor Chip for Wavelength-based Surface Plasmon Resonance Biosensor

Alom, Azharul; Prabowo, Briliant Adhi; Chang, Ya Ju; Liu, Kou−Chen

doi:10.1364/fts.2019.jth2a.34

Cited by 2 publications

(1 citation statement)

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“…Specific sensing applications demand sensors having a high figure of merit. Studies on sensors with metallic multilayers have been reported to yield some positive results. ,− Sensors with multilayers of different metals combine the features of each metal, and this undoubtedly reflects in parameters like the position and shift of the resonant wavelength as well as the spectral width and depth of the SPR curve. This opens new options for designing fiber-optic biosensors.…”

Section: Introductionmentioning

confidence: 99%

Surface Plasmon Resonance-Based Fiber-Optic Metallic Multilayer Biosensors

2021

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Accurate and quick sensing of various biomolecules relevant to different health conditions is indispensable in modern diagnosis and treatment procedures. Different multilayer metallic surface plasmon resonance (SPR) biosensor configurations comprising Au, Ag, Al, and Cu are analyzed in this work by employing an N -layer matrix formalism as applied to the fixed-angle spectral SPR sensing methodology. Stringent standards for sensitivity, detection accuracy, and figure of merit (FOM) of the sensor configurations are set to analyze the relative merits of one configuration over another. It is observed that three- and four-layer configurations using Al and Cu provide the best FOM among all sensors that passed the set standard criteria. The highest FOM (1433.82/RIU) is observed for the four-layer Al/Cu/Al/Cu sensor for an analyte refractive index of 1.408. The sensors are best suited for detecting analytes with a refractive index range of 1.350–1.414.

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