Four new compounds from fruits of Hypericum patulum Thunb.

Abstract

A new naphthoquinone, patulumnaphthoquinone A (1) and three new glycosides, patulumside B (2), patulumside C (3) and patulumside D (4) were isolated from the 30% ethanol extract of the fresh ripe fruits of Hypericum patulum Thunb. using column chromatography techniques. The structures of these compounds including absolute configurations were elucidated on the basis of HRESIMS, NMR spectroscopic analyses, calculated electronic circular dichroism spectra and comparison with the literatures.