Four Primary Malignant Tumors, Including Malignant Melanoma and Malignant Lymphoma, in the Same Adult Patient

Abstract

We report an 80-year-old Japanese male with four primary malignant tumors: malignant melanoma, prostatic cancer, malignant lymphoma, and renal cell carcinoma, which occurred in that respective order. The combination of malignant melanoma and malignant lymphoma is rare. The patient was treated with BeG after an operation for malignant melanoma. He was also treated with cobalt 60 irradiation after an operation for prostatic cancer. We also discuss other reports of multiple malignant tumors and suggest some possible causes of this patient's primary malignant tumors.

A Case of CD8+ T Cell Lymphoma Occurring during Treatment for In situ Malignant Melanoma of the Palate

“…Malignant melanoma. (MM) is rarely accompanied by malignant lymphoma (ML); less than 10 cases of their association, including two Japanese cases (1,2), have been reported. In most of the previously published cases, the two tumors appeared in anatomically distant regions and were accompanied by characteristic clinical symptoms.…”