Four-year outcome of moderate left main disease: intravascular ultrasound predictor of events

Prospective Application of Pre-Defined Intravascular Ultrasound Criteria for Assessment of Intermediate Left Main Coronary Artery Lesions

“…EEM ϭ external elastic membrane; LA ϭ lumen area; LD ϭ lumen diameter; MLA ϭ minimum lumen area. burden to be the only independent predictor of cardiac events (11). The Mayo Clinic group reported a series of 214 patients recruited in an 8-year period in which the cutoff value for MLA was 7.5 mm 2 (9).…”

2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention

“…A minimal lumen area Ͼ7.5 mm 2 suggests that revascularization may be safely deferred (490). A minimal lumen area between 6 and 7.5 mm 2 requires further physiological assessment, such as measurement of FFR (487,500). For non-left main stenoses, minimal lumen diameter Ͼ2.0 mm and minimal lumen area Ͼ4.0 mm 2 correlate with low event rates (489).…”

Intravascular Ultrasound for the Diagnosis and Treatment of Left Main Coronary Artery Disease

“…Importantly, plaque burden was the only predictor of events at the 5-year follow-up for LMCA lesions left untreated. 21 The strengths and limitations of IVUS and FFR to assess the severity of ambiguous left main lesions are summarized in Table 2. It may be useful to select the modality of basal LMCA assessment based on several criteria.…”