Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling

Kalkman, Jeroen

doi:10.1155/2017/9586067

Cited by 36 publications

(26 citation statements)

References 39 publications

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“…The lateral resolution in an OCT imaging system is a function of the central wavelength and the numerical aperture of the imaging system and is decoupled from its axial resolution. For more in-depth discussions and analysis of OCT image formation, we refer the readers to many articles and books including but not limited to [33,[35][36][37][38][39][40][41][42][43][50][51][52][53].…”

Section: Materials and Methods: Theorymentioning

confidence: 99%

Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner

Atry

Rosa

Rarick

et al. 2018

International Journal of Optics

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In the past decades, spectral-domain optical coherence tomography (SD-OCT) has transformed into a widely popular imaging technology which is used in many research and clinical applications. Despite such fast growth in the field, the technology has not been readily accessible to many research laboratories either due to the cost or inflexibility of the commercially available systems or due to the lack of essential knowledge in the field of optics to develop custom-made scanners that suit specific applications. This paper aims to provide a detailed discussion on the design and development process of a typical SD-OCT scanner. The effects of multiple design parameters, for the main optical and optomechanical components, on the overall performance of the imaging system are analyzed and discussions are provided to serve as a guideline for the development of a custom SD-OCT system. While this article can be generalized for different applications, we will demonstrate the design of a SD-OCT system and representative results for in vivo brain imaging. We explain procedures to measure the axial and transversal resolutions and field of view of the system and to understand the discrepancies between the experimental and theoretical values. The specific aim of this piece is to facilitate the process of constructing custom-made SD-OCT scanners for research groups with minimum understanding of concepts in optical design and medical imaging.

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Section: Materials and Methods: Theorymentioning

confidence: 99%

Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner

Atry

Rosa

Rarick

et al. 2018

International Journal of Optics

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“…The FD-OCT [39] uses the same operating principle of low coherence interferometry and is generally implemented with a Michelson interferometer shown in Figure 3, this OCT systems are based on a measurement of the interference spectrum ether in space on a spectrometer (spectral domain) or in time with a wavelength sweep (swept-source). The basic operation is similar to that described above.…”

Section: A Interferencementioning

confidence: 99%

Optical methods for measuring corneal topography: A review

Jalife-Chavira¹,

Trujillo-Shiaffino²,

Mendoza-Villegas³

et al. 2019

Opt. Pura Apl.

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The cornea is the outermost surface of the eyeball; and has almost 70% of the eyes total refractive power, what makes it essential for the human vision process. However, some pathologies and refractive errors modify normal functions of the cornea, decreasing visual acuity along with the individual's quality of life. Thus, in the presence of ametropia, an appropriate diagnosis, treatment, and corrections of cornea's dimensions is vital. Nowadays, several methods to retrieve corneal topography are available. In this paper, the most relevant techniques in the field are presented.

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“…The OCT signal is simulated with the assumption of 1-dimensional light propagation in the single scattering approximation [28]. In brief, a turbid medium is simulated by propagating the sample field for every wavenumber inside the random medium using a light propagation model based on a discrete medium with Mie scattering particles.…”

Section: Oct Simulationsmentioning

confidence: 99%

Segmentation of thin corrugated layers in high-resolution OCT images

Callewaert¹,

Dik²,

Kalkman³

2017

Opt. Express

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Abstract:In this paper we present a novel method for the segmentation of thin corrugated layers in high resolution optical coherence tomography (OCT) images. First, we make an initial segmentation, for example with graph based segmentation that, for highly corrugated interfaces, leads to many segmentation errors. Second, we resegment the initial outcome, based on the OCT attenuation coefficient image with our matching layer attenuation coefficient segmentation (MLAS) algorithm. This algorithm repositions the initial segmentation such that it finds the point where the attenuation coefficient is close to the mean centerline attenuation. The algorithm does not utilize any sample specific prior knowledge in the attenuation coefficient based segmentation step. For simulated and measured data of strongly corrugated samples, such as is the case for varnish layers on paintings and furniture, the MLAS algorithm performs much better than the conventional segmentation. Finally, we show 3D segmentation of 190 mm 3 OCT volume of a thin corrugated varnish layer. Our technique can aid in the rapid characterization of layer stratigraphy and deepen our understanding of their condition.

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Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling

Cited by 36 publications

References 39 publications

Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner

Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner

Optical methods for measuring corneal topography: A review

Segmentation of thin corrugated layers in high-resolution OCT images

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