Fourier photoacoustic microscope improved resolution on single-pixel imaging

Abstract

A new single-pixel Fourier photoacoustic microscopy (PAM), to the best of our knowledge, is proposed to improve the resolution and region of interest (ROI) of an acquired image. In the previous structure of single-pixel Fourier PAM, called spatially invariant resolution PAM (SIR-PAM), the lateral resolution and ROI are limited by the digital micromirror device (DMD) pixel size and the number of pixels. This limitation is overcome here through illuminating fixed angle interfering plane waves, changing the fringe frequency via varying the frequency of the laser source. Given that the fringe sinusoidal patterns here can be produced by two mirrors, the DMD usage can be omitted. In this way, the fringe frequency can be changed in a wider spectrum, making it possible to capture a wider spectral bandwidth and thus a higher-resolution image. Also, the removal of the ROI limitation results in a high-resolution frequency-swept PAM structure. Monte Carlo simulations show 1.7 times improvement in lateral resolution compared to SIR-PAM based on the point-spread function and full-width-at-half-maximum.

Comparison of Common Algorithms for Single-Pixel Imaging via Compressed Sensing

“…Thus, to improve the imaging resolution, the integration of the detector needs to be increased, which leads to higher requirements for manufacturing. Single-pixel imaging (SPI) [ 1 , 2 ] uses a single-pixel detector, instead of a detector array with a lot of pixels in traditional imaging, to realize two-dimensional or even multi-dimensional imaging, which gives cost-efficiency to broadband imaging and resolution enhancement, and recently has a lot of attention with the potential of applications in various imaging areas such as visible range imaging [ 3 ], multispectral imaging [ 4 , 5 , 6 , 7 ], hyperspectral imaging [ 8 ], ultrafast imaging [ 9 ], infrared imaging [ 10 ], terahertz imaging [ 11 , 12 , 13 ], gas imaging [ 14 ], microscopic imaging [ 15 , 16 , 17 ], imaging through scattering media [ 18 , 19 ], photoacoustic imaging [ 20 ], long-range imaging [ 21 , 22 ], X-ray imaging [ 23 , 24 ], 3D imaging [ 25 ] and holography [ 26 ], etc.…”