In this paper, we consider the global well-posedness and time-decay rates of solution to the Cauchy problem for 3D convective Cahn-Hilliard equation with doublewell potential via a refined pure energy method. In particular, the optimal decay rates of the higher-order spatial derivatives of the solution are obtained, theḢ −s (0 < s ≤ 1 2 ) negative Sobolev norms is shown to be preserved along time evolution and enhance the decay rates.2010 Mathematics Subject Classification. 35Q35, 35B65, 76N10, 76D05.