In this paper, a cascaded fractional Kalman filter for state of charge and branch current estimation of largescale battery systems is proposed. As a centralized approach for the estimation of a large-scale system is costly in terms of effort and time, a partition into smaller and, therefore, simpler subsystems is applied. Since the overall system is divided into smaller units, a local computation is allowed and complexity reduced. In these distributed systems, usually, the subsystems communicate with each other to exchange relevant data. Using a model based on mesh currents, we receive a cascaded system structure which results in a hierarchical arrangement of all subsystems. This concludes in a one-directional information flow and, therefore, reduces the overall communication effort. Using this proposed approach, it is not only possible to estimate the states of each branch locally but also to calculate the branch currents when the total current is known. Finally, a practical test with real measurement data is presented.