This paper collects results concerning global rates and large time asymptotics of a fractional fast diffusion on the Euclidean space, which is deeply related with a family of fractional Gagliardo-Nirenberg-Sobolev inequalities. Generically, self-similar solutions are not optimal for the Gagliardo-Nirenberg-Sobolev inequalities, in strong contrast with usual standard fast diffusion equations based on non-fractional operators. Various aspects of the stability of the self-similar solutions and of the entropy methods like carré du champ and Rényi entropy powers methods are investigated and raise a number of open problems.