Fractional Photothermolysis for the Treatment of Striae Distensae in Asian Skin

Kim, Beom Joon; Lee, Dong Hun; Kim, Myeung Nam; Song, Kye Yong; Cho, Wan Ik; Lee, Chang Kyun; Kim, Jo Yong; Kwon, Oh Sang

doi:10.2165/00128071-200809010-00003

Cited by 126 publications

(93 citation statements)

References 1 publication

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“…A substantial improvement in the appearance of the striae and a partial normalization of skin elasticity were shown 8 weeks after treatment. Biopsies revealed a significant increase in epidermal thickness, collagen, and elastic fiber deposition after FP [31]. One patient with poikiloderma of Civatte showed complete resolution of the pigmentary changes after one FP treatment at 8 mJ/cm 2 with 2,000 MTZs per square centimeter [32].…”

Section: Non-ablative Fractional Photothermolysis Lasermentioning

confidence: 97%

Fractional photothermolysis—an update

Allemann¹,

Kaufman

2009

Lasers Med Sci

135

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The novel concept of non-ablative fractional photothermolysis was introduced to the market in 2003 as an answer to the need for effective, yet low risk, resurfacing techniques. Unlike conventional ablative and non-ablative lasers, fractional ablative and non-ablative photothermolysis treats only a fraction of the skin, leaving up to a maximum of 95% of the skin uninvolved. The undamaged surrounding tissue allows for a reservoir of viable tissue, permitting rapid epidermal repair. Non-ablative fractional photothermolysis is currently approved by the US Food and Drug Administration (FDA) for the treatment of pigmented lesions, periorbital rhytides, skin resurfacing, melasma and soft tissue coagulation, acne and surgical scars, and actinic keratoses. However, its off-label use is clearly more extended. In 2007 the concept was further developed, and ablative fractional photothermolysis was introduced, using an erbium yttrium aluminium garnet (Er: YAG) or carbon dioxide laser. These devices are FDA cleared to treat wrinkles, rhytides, furrows, fine lines, textural irregularities, pigmented lesions and vascular dyschromia. In this review we discuss the two concepts, their technical details and clinical indications, and we describe the current literature available. Abstract The novel concept of non-ablative fractional photothermolysis was introduced to the market in 2003 as an answer to the need for effective, yet low risk, resurfacing techniques. Unlike conventional ablative and non-ablative lasers, fractional ablative and non-ablative photothermolysis treats only a fraction of the skin, leaving up to a maximum of 95% of the skin uninvolved. The undamaged surrounding tissue allows for a reservoir of viable tissue, permitting rapid epidermal repair. Non-ablative fractional photothermolysis is currently approved by the US Food and Drug Administration (FDA) for the treatment of pigmented lesions, periorbital rhytides, skin resurfacing, melasma and soft tissue coagulation, acne and surgical scars, and actinic keratoses. However, its off-label use is clearly more extended. In 2007 the concept was further developed, and ablative fractional photothermolysis was introduced, using an erbium yttrium aluminium garnet (Er: YAG) or carbon dioxide laser. These devices are FDA cleared to treat wrinkles, rhytides, furrows, fine lines, textural irregularities, pigmented lesions and vascular dyschromia. In this review we discuss the two concepts, their technical details and clinical indications, and we describe the current literature available.

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Section: Non-ablative Fractional Photothermolysis Lasermentioning

confidence: 97%

Fractional photothermolysis—an update

Allemann¹,

Kaufman

2009

Lasers Med Sci

135

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“…In study [76] along with a significant improvement of the appearance of striae by 8 weeks after the treatment with non-ablative FP there was a considerable increase in the thickness of the epidermis as well as a recovery of the tissue elasticity.…”

Section: Reviewsmentioning

confidence: 79%

“…In the long-term follow-up (from 6 months to 2 years) the average reduction of the acne was between 72 and 75%. A number of studies [75,76] have indicated not only a considerable improvement in skin defects but also a general recovery of the surrounding tissues after non-ablative FP.…”

Section: Reviewsmentioning

confidence: 99%

Fractional Laser Photothermolysis in the Treatment of Skin Defects: Possibilities and Effectiveness (Review)

Karabut¹,

Gladkova²,

Feldchtein³

2016

Sovrem Tehnol Med

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Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russian Federation For skin defect treatment and rejuvenation the ablative laser skin resurfacing with a CO 2 laser is widely applied in cosmetology and dermatology. However this treatment can result in the risk of undesirable side effects and requires a long-term recovery after the procedure. When non-ablative laser skin rejuvenation is used as an alternative, the level of safety is increased, however the efficacy of the procedure is considerably reduced.The use of fractional laser photothermolysis is a particularly important step in the development of laser technology for cosmetology and dermatology. Due to the creation of only microscopic areas of thermal damage under the laser exposure, this method results in safe, quick healing and complete recovery of the skin without any undesirable side effects. The review presented here illustrate the high efficacy of the application of both ablative and non-ablative fractional laser photothermolysis for wrinkles reduction, for general improvement of the skin appearance, for the abnormal pigmentation treatment, and the removal or appearance improvement of atrophic scars from acne as well as in areas of skin stretching (striae).Key words: laser technologies in cosmetology; ablative and non-ablative laser exposure; fractional laser photothermolysis.For contacts: Maria M. Karabut,

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“…Lasers represent another option in treating striae and have minimal side effects but a moderately beneficial effect [8] [9]. Minimal pain and post treatment hyperpigmentation were the main adverse events reported in some clinical trials with lasers [10]. Abdominoplasty is a cosmetic surgery procedure used to make the abdomen thinner and more firm but it carries certain risks that may be serious or life-threatening [11].…”

mentioning

confidence: 99%

Carbocysteine: A New Way for Stretch Marks Treatment

Scarci¹,

Mailland²

2015

JCDSA

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Background/Purpose: Although stretch marks (or striae) do not represent a medical problem, they are considered as the cause of psychological distress for women of any age that need to be treated. There are many cosmetic products or procedures claiming to improve the appearance of striae, but most of them are able to affect only striae appearance rather than physical characteristics or, even worse, they are provided with untoward effects. Our aim was to find a more efficacious and safe alternative to the existing tools. Methods: A randomized, blind observer study was conducted on 33 women to test the efficacy and safety of P-3059, a new product containing carboxymethylcysteine, Vitamin E and sweet almond oil. P-3059 was applied twice daily for 8 weeks and it was tested intra-subject in a split-body design versus an untreated area (negative control), comparing two symmetric areas with striae selected on the body/legs of each subject. The main study endpoint was the visual evaluation of striae, by means of the validated POSAS scale (consisting of two parts, OSAS and PSAS), at the end of treatment in comparison with baseline. Results: The comparison of the individual parameters of OSAS, showed significantly improved mean values for striae thickness, relief and pliability at the end of treatment (p < 0.05). The PSAS evaluation showed a statistically significant benefit in the improvement in thickness of the striae towards that of normal skin (p < 0.044). Conclusion: The new product based on carboxymethylcysteine leads to an improvement in the appearance and in the physical characteristics of striae, reducing their thickness and improving relief and pliability, as well as subjects satisfaction.

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Fractional Photothermolysis for the Treatment of Striae Distensae in Asian Skin

Abstract: FP can reduce SD by stimulating new collagen and elastic fiber synthesis. In addition, repetitive treatments might constitute an effective approach to improving the treatment of SD.

Cited by 126 publications

References 1 publication

Fractional photothermolysis—an update

Fractional photothermolysis—an update

Fractional Laser Photothermolysis in the Treatment of Skin Defects: Possibilities and Effectiveness (Review)

Carbocysteine: A New Way for Stretch Marks Treatment

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