This study explores the enhancement of wireless communication through the integration of OFDM with MIMO and advanced techniques like COFDM, adaptive MIMO, and beamforming. It evaluates a 2×2 and 4×4 MIMO-DWPT-COFDM system, considering modulation (BPSK and QPSK) and equalization (ZF-SIC and MMSE-SIC) over a Rayleigh fading channel. MATLAB results reveal that more antennas, BPSK modulation, and MMSE-SIC equalization significantly improve BER performance. Specifically, for a BER of 10−4, the 2×2 MIMO system requires E
b / N
0 values of 10.4 (MMSE-SIC) and 11.4 (ZF-SIC), while the 4×4 MIMO system needs 5.5 (MMSE-SIC) and 5.9 (ZF-SIC). These findings emphasize the need for thoughtful system design and parameter optimization in achieving reliable and efficient wireless communication.