Fractionated Er:YAG laser versus fully ablative Er:YAG laser for scar revision: Results of a split scar, double blinded, prospective trial

Tidwell, W. James; Owen, Cindy E.; Kulp‐Shorten, Carol L.; Maity, Abhishek; McCall, Michael W.; Brown, Timothy S.

doi:10.1002/lsm.22562

Cited by 23 publications

(16 citation statements)

References 14 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The clinical trials demonstrated a significant improvement in scar appearance . Due to decreased erythema and pruritus , multiple laser wavelengths have been used to manage scars, including argon (514 nm), pulsed dye laser (595 nm), Nd:YAG (1064 nm), Er: YAG, and carbon dioxide (10.6 μm) . The 595 nm pulsed dye laser is commonly used for the HTS treatment due to low risk of side effects and complications .…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluations of hypertrophic scar formation in in vivo models

Kim

Kang

2018

Lasers Surg Med

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Comparative evaluations of hypertrophic scar formation in in vivo models

Kim

Kang

2018

Lasers Surg Med

View full text Add to dashboard Cite

show abstract

“…Ablative fractional laser treatment improves the quality and appearance of skin and scars , but offers minor improvement in skin laxity compared with surgical excision and lifting operations, even when a comparable amount of skin has been removed. Ablative fractional laser treatment provides a potent stimulus for skin remodeling, but is conceptually equivalent to leaving thousands of small open wounds without primary closure.…”

Section: Discussionmentioning

confidence: 99%

Significant skin‐tightening by closure of fractional ablative laser holes

et al. 2017

View full text Add to dashboard Cite

Background and Objective Ablative fractional laser treatment uses thousands of very small laser beam wounds to damage a fraction of the skin, which stimulates tissue remodeling. Each open micro‐wound heals without scarring, but the amount of skin tightening achieved is limited. This animal study was performed to test the hypothesis that immediate temporary closure of fractional laser wounds could increase skin tightening after fractional ablative laser treatment. Materials and Methods Four adult swine were used for the study; 98 square test sites (3 × 3 cm) were tattooed on the abdomen and flanks of each pig. An ablative fractional Erbium:YAG laser (Sciton Profile, Sciton Inc, Palo Alto, CA) was used to treat the test areas. A laser micro‐spot fluence of 375 J/cm2 was delivered in 150–250 microseconds pulses, resulting in an array of ablation channels extending 1.5 mm deep into the skin, with a spot size of 250 µm, with 10% treatment density. Immediately following laser exposure the resulting holes were closed using a stretched elastic adhesive dressing, which, when applied, recoiled and compressed the diameter of the ablation holes. The compressive dressings were removed after 7 days. This procedure was compared to removing the same amount of skin (10%) mechanically by specially designed 19 gauge coring needles, as well as to the same laser and coring methods without compression closure. Area and shape of test sites were measured by digital photography before and 28 days after treatment. Data analysis included compensation for animal growth, as measured by increase in the area of the untreated control sites. Results All treated and control sites healed within a week, without scarring evident at 28 days. Laser treatment combined with compressive wound closure caused significant shrinkage at 28 days compared with untreated control sites. The treated skin area was reduced by 11.5% (P = 0.0001). Needle coring with wound closure produced similar, significant shrinkage (8%, P < 0.0021), whereas laser and needle coring treatment without closure did not result in significant area reduction (P = 0.1289) compared with untreated control sites. Conclusion Significant skin tightening can be achieved by immediate temporary non‐invasive wound closure after short pulse Er:YAG fractional ablative laser treatment, as well as after mechanically removing skin with a coring needle. This approach may improve skin tightening after ablative laser treatments. Further clinical studies are necessary to confirm successful application in humans. Lasers Surg. Med. 50:64–69, 2018. © 2017 Wiley Periodicals, Inc.

show abstract

“…Fractional laser therapy with either non-ablative or fully ablative lasers has been shown to improve the color, texture, thickness and patient satisfaction of atrophic surgical scars [31][32][33] . These lasers are effective because they stimulate neocollagenesis and dermal remodeling.…”

Section: Atrophic Scarsmentioning

confidence: 99%