Fractionation of poly(dimethyl siloxane) by interaction chromatography

Abstract

Poly(dimethyl siloxane) (PDMS) was characterized by interaction chromatography using C4-bonded silica and a mixture of THF/CH 3 OH as the stationary phase and the mobile phase, respectively. Under the separation condition, a commercial PDMS with broad molecular weight distribution was successfully fractionated according to molecular weight into fractions with a very narrow molecular weight distribution. The IC separation could be applied to more rigorous characterization of PDMS, modified PDMS, and block copolymer-containing PDMS.

Comparison of Molar Mass Determination of Poly(dimethylsiloxanes) by Size Exclusion Chromatography and High-Resolution Polymer High Performance Liquid Chromatography Based on a Sawtooth Gradient

“…For instance, they applied TGIC for the separation of polyvinyl chloride up to a molar mass of 1,800,000 g•mol −1 by only changing the column temperature from 25 to 48 °C23 or the analysis of anionic polymerized PDMS samples. 24 Each technique has its own advantages and disadvantages; however, this study focuses on comparing SEC and polymer HPLC in combination with sawtooth gradients. Further information concerning LCCC can be found in refs 25−28.…”

“…Another possibility improving polymer separation with liquid chromatography was introduced by Chang and co-workers , and is called temperature gradient interaction chromatography (TGIC). For instance, they applied TGIC for the separation of polyvinyl chloride up to a molar mass of 1,800,000 g·mol –1 by only changing the column temperature from 25 to 48 °C or the analysis of anionic polymerized PDMS samples . Each technique has its own advantages and disadvantages; however, this study focuses on comparing SEC and polymer HPLC in combination with sawtooth gradients.…”

Mechanistic Pathway for the Formation of Radial Polystyrenes Using Diacyl Chloride

“…The resolution in SEC is not as good for branched polymers as linear polymers because the hydrodynamic chain size does not increase with the molecular weight as significantly as with linear polymers. For a more rigorous characterization of branched polymers, interaction chromatography (IC) is preferred and shows much higher resolution. − Mass spectrometry (MS) is a valuable technique for the analysis and identification of low molecular weight polymers with different end groups. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI–TOF MS) has made the analysis of these low molecular weight polymers possible for a wide variety of polymers that have rarely been directly analyzed by mass spectrometric methods. − This soft ionization method has become the most widely used MS technique in polymer analyses because it is applicable to a greater variety of synthetic polymers than any other MS method leading to simple spectra, displaying only singly charged quasi-molecular ions with little or no fragmentation. − The present study on the new star polystyrenes utilizes MALDI–TOF MS for the structure elucidation and end-group analysis of star polystyrenes synthesized by living anionic polymerization.…”

Polydimethylsiloxane-Paper Hybrid Lateral Flow Assay for Highly Sensitive Point-of-Care Nucleic Acid Testing

“…In the present study, we demonstrate a novel strategy of incorporating a paper-based shunt and a polydimethylsiloxane (PDMS) barrier into the strip. PDMS was selected, because it is inexpensive, inert, nontoxic, and (unlike wax suggested by the existing studies , ) heat-resistant, complementing the heating process normally required for sample-to-answer NAT. Interestingly, we found that creating a PDMS barrier alone would not sufficiently enhance the signal whereas implementing a larger shunt alone would be sample-consuming.…”