A series of multiaxial tests on an industrial acrylonitrilebutadiene-styrene (ABS) tube were conducted at room temperature. The ratcheting strain accumulation was found to be closely related to the shear strain amplitude and axial mean stress. The ratcheting strain and its rate increased with increasing shear strain amplitude as well as axial mean stress. At the same time, the ratcheting strain accumulation was retarded with a negative mean stress, and the ratcheting shakedown appeared when the negative mean stress reached 210 MPa. To understand the influences of loading history on axial ratcheting strain, a series of multistep loading tests under constant symmetrical torsion at different axial mean stresses of 5, 0, and 25 MPa were performed. The results showed that both the compressive viscous strain and strain relaxation of ABS could lead to the decrease of axial ratcheting strain. Furthermore, the compressive viscous strain and strain relaxation are independent of the loading history. Considering the influence of mean stress, a modified fatigue life model based on the Basquin law was presented to predict the pure torsional fatigue and multiaxial fatigue of ABS. The results of the modified fatigue life model show it can give relatively accurate fatigue life predictions. POLYM. ENG. SCI., 55:664-671, 2015.