Background: Osteoporosis is an increasing health problem in Indonesia. Fractures that occur in the spine and pelvis are considered to be the most common fracture sites for osteoporosis. Aim: to determine the differences in bone mineral density values in postmenopausal women with fracture and non-fracture. Methods: Survey was carried out in postmenopausal female patients with fractures and without fractures who were included in the inclusion criteria with a case-control study approach and had bone mass density data. For the group of cases with fracture, the amount of vertebral compression was measured using Gennant's measurement criteria. Interviews were conducted regarding the characteristics of patients with and without fracture. The differences in BMD values were analyzed in postmenpausal female patients with fracture and without fracture by using unpaired T test on normal data distribution and Mann-Whitney test on abnormal data distribution. The measured BMD value is the T-score. The analysis result was considered significant if p <0.05. Results: There was a significant difference between L4 BMD (p = 0.029) and femoral neck BMD (p = 0.014) in postmenopausal female patients with fracture and without fracture. However, there were no significant differences for other BMD regions (p> 0.5). Conclusion: BMD L4 and femoral neck values differ significantly in female patients with postmenopausal osteopenia with fracture and non-fracture.