2024
DOI: 10.1021/acsnano.4c03874
|View full text |Cite
|
Sign up to set email alerts
|

Fragile Guts Make Fragile Brains: Intestinal Epithelial Nrf2 Deficiency Exacerbates Neurotoxicity Induced by Polystyrene Nanoplastics

Boxuan Liang,
Yanhong Deng,
Yuji Huang
et al.

Abstract: Oral ingestion is the primary route for human exposure to nanoplastics, making the gastrointestinal tract one of the first and most impacted organs. Given the presence of the gut− brain axis, a crucial concern arises regarding the potential impact of intestinal damage on the neurotoxic effects of nanoplastics (NPs). The intricate mechanisms underlying NP-induced neurotoxicity through the microbiome−gut−brain axis necessitate further investigation. To address this, we used mice specifically engineered with nucl… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
references
References 61 publications
0
0
0
Order By: Relevance