Fragmentation of Pamam Dendrimers in Methanol

Peterson, Janek; Allikmaa, Veiko; Pehk, Tõnis; Lopp, Margus

doi:10.3176/chem.2001.3.06

Cited by 10 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Side reactions during the synthesis of dendrimers often cause defects in their structure. The literature [ 30 , 31 ] describes both the range of possible side reactions and the main methods for preventing their occurrence.…”

Section: Resultsmentioning

confidence: 99%

PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding

Mostovaya

Padnya

Shiabiev

et al. 2021

IJMS

View full text Add to dashboard Cite

A convenient method for the synthesis of the first generation PAMAM dendrimers based on the thiacalix[4]arene has been developed for the first time. Three new PAMAM-calix-dendrimers with the macrocyclic core in cone, partial cone, and 1,3-alternate conformations were obtained with high yields. The interaction of the obtained compounds with salmon sperm DNA resulted in the formation of the associates of the size up to 200 nm, as shown by the UV-Vis spectroscopy, DLS, and TEM. It was demonstrated by the CD method that the structure of the DNA did not undergo significant changes upon binding. The PAMAM-calix-dendrimer based on the macrocycle in cone conformation stabilized DNA and prevented its degradation.

show abstract

Section: Resultsmentioning

confidence: 99%

PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding

Mostovaya

Padnya

Shiabiev

et al. 2021

IJMS

View full text Add to dashboard Cite

show abstract

Tandem mass spectrometry of half‐generation PAMAM dendrimer anions

McLuckey

2004

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

Ions derived from negative electrospray ionization of polyamidoamine (PAMAM) dendrimer generation 0.5 were subjected to ion trap tandem mass spectrometry. Ion/ion proton transfer reactions were used to manipulate the charge states of PAMAM precursor ions to form lower charge states from those initially formed by electrospray, as well as to facilitate the interpretation of the product ion mass spectra. Most of the products derived from dendrimer precursor ions could be rationalized by retro-Michael decomposition reactions. The dominant fragmentation channels are highly dependent on the composition of the counter-ions, which in this case are restricted to different numbers of sodium ions and protons, and whether the precursor ion is multiply charged or singly charged. An interpretation is given that is consistent with all of the observations made with the various anions associated with this study. The nature of the structural information that can be obtained via ion trap tandem mass spectrometry of the dendrimers is dependent on the types of precursor ions subjected to study. The tandem mass spectrometry data also provided information about the structure of faulty synthesis products present in the PAMAM dendrimer sample.

show abstract

Synthesis and catalytic evaluation of dendrimer-templated and reverse microemulsion Pd and Pt nanoparticles in the reduction of 4-nitrophenol: The effect of size and synthetic methodologies

Noh

Meijboom

2015

Applied Catalysis A: General

View full text Add to dashboard Cite

Fragmentation of Pamam Dendrimers in Methanol

Cited by 10 publications

References 2 publications

PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding

PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding

Tandem mass spectrometry of half‐generation PAMAM dendrimer anions

Synthesis and catalytic evaluation of dendrimer-templated and reverse microemulsion Pd and Pt nanoparticles in the reduction of 4-nitrophenol: The effect of size and synthetic methodologies

Contact Info

Product

Resources

About