Frailty and Sarcopenia in Primary Care: Current Issues

Bracchitta, Luigi Maria; Angioni, Daniele; Celotto, Stefano; Cesari, Matteo

doi:10.1007/978-3-030-78923-7_10

Cited by 1 publication

(1 citation statement)

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“…Although there is a general consensus regarding the theoretical definition of frailty as a multidimensional and dynamic condition characterized by a loss of reserve across multiple physiological systems which collectively result in a compromised resilience to cope with stressors [ 17 , 18 , 19 , 20 , 36 , 44 , 45 , 46 , 47 , 48 , 49 , 50 ]. Presently, there is no one universally utilized or accepted operational definition for the classification of frailty [ 27 , 51 , 52 ].…”

Section: Introductionmentioning

confidence: 99%

Frailty: Pathophysiology, Theoretical and Operational Definition(s), Impact, Prevalence, Management and Prevention, in an Increasingly Economically Developed and Ageing World

Doody¹,

Lord²,

Greig³

et al. 2022

Gerontology

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The world’s population is ageing, and most older adults experience a later life burdened with disease and disability. Frailty is a multi-dimensional and dynamic condition characterised by declines in reserve and function across multiple physiologic systems, such that the ability to cope with every day or acute stressors becomes compromised. It is projected to become one of the most serious public health challenges economically developed societies will face in the coming century. This review provides a comprehensive overview of frailty, exploring its pathophysiology, theoretical and operational definition(s), impact, prevalence, management, and prevention, within the context of its emergence as a major public health challenge, in an increasingly economically developed and ageing world. Further, this review discusses the major limitations, deficiencies, and knowledge gaps presently within the field, and future research directions pertinent to the advancement of frailty research and the promotion of healthy longevity among the increasing global population of older adults.

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